Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 10/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20959807 | 1.00 | FAAH (0.52) | FAAHEPHX1CASP2CNR2ZDHHC20 | |
| SCHEMBL18843429 | 1.00 | FAAH (0.52) | FAAHEPHX1CASP2CNR2ZDHHC20 | |
| SCHEMBL29441797 | 1.00 | FAAH (0.52) | FAAHEPHX1CASP2CNR2ZDHHC20 | |
| SCHEMBL11152873 | 1.00 | FAAH (0.52) | FAAHEPHX1CASP2CNR2ZDHHC20 | |
| SCHEMBL11318606 | 1.00 | FAAH (0.52) | FAAHEPHX1CASP2CNR2ZDHHC20 | |
| SCHEMBL19970455 | 1.00 | FAAH (0.52) | FAAHEPHX1CASP2CNR2ZDHHC20 | |
| SCHEMBL23528236 | 1.00 | FAAH (0.52) | FAAHEPHX1CASP2CNR2ZDHHC20 | |
| SCHEMBL11329413 | 1.00 | FAAH (0.52) | FAAHEPHX1CASP2CNR2ZDHHC20 | |
| SCHEMBL28396415 | 0.98 | FAAH (0.50) | FAAHEPHX1CASP2CNR2ZDHHC20 | |
| SCHEMBL29129919 | 0.98 | FAAH (0.50) | FAAHEPHX1CASP2CNR2ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377473-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |