Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20476357 | 0.82 | MAPT (0.41) | KMT2AMAPTMEN1ESR1ESR2 | |
| SCHEMBL28699641 | 0.77 | NPC1 (0.55) | KMT2AMAPTMEN1ESR1ESR2 | |
| SCHEMBL28678174 | 0.74 | MAPT (0.47) | KMT2AMAPTMEN1ESR1ESR2 | |
| SCHEMBL28696745 | 0.74 | MAPT (0.47) | KMT2AMAPTMEN1ESR1ESR2 | |
| SCHEMBL29237794 | 0.73 | MAPT (0.49) | KMT2AMAPTMEN1ESR1ESR2 | |
| SCHEMBL28681175 | 0.71 | L3MBTL1 (0.48) | KMT2AMAPTMEN1ESR1ESR2 | |
| SCHEMBL20503270 | 0.71 | SMN1; SMN2 (0.39) | KMT2AMAPTMEN1L3MBTL1KDM4E | |
| SCHEMBL28677210 | 0.70 | NPC1 (0.48) | KMT2AMAPTMEN1ESR1ESR2 | |
| SCHEMBL28550468 | 0.69 | SRD5A2 (0.46) | KMT2AMAPTMEN1HTTKDM4E | |
| SCHEMBL5532478 | 0.69 | ACACB (0.45) | KMT2AMAPTMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3377473-A1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX Pharmaceuticals, Inc. (US) | 2018-09-26 | — | — | EP | disclosed |