Glyoxylate

Glyoxylate

SCHEMBL20503553

FC=C(F)F.O=CC(=O)O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
TP53 P04637 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
EGLN3 Q9H6Z9 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL705476 0.82
Glyoxylate SCHEMBL15868 0.78
Acrylic Acid SCHEMBL3902257 0.78 LMNA (0.62) TSHRTP53EGLN1EGLN3LMNA
Glyoxylate SCHEMBL11690306 0.78 TSHR (0.50) TSHRTP53EGLN1EGLN3LMNA
Glyoxylate SCHEMBL1518069 0.78 TSHR (0.50) TSHRTP53EGLN1EGLN3LMNA
Acetic Acid SCHEMBL28027727 0.76
Tetrafluoroethylene SCHEMBL29010219 0.76 CA1 (0.36)
Glyoxylate SCHEMBL25410023 0.73
Glyoxylate SCHEMBL2452312 0.73
Glyoxylate SCHEMBL3596615 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3377612-A1 FUNCTIONAL EXPRESSION OF MONOOXYGENASES AND METHODS OF USE Industrial Microbes, Inc. (US) 2018-09-26 EP disclosed