SCHEMBL20503622

SCHEMBL20503622

C=CC(=O)NCCCCCCCCCCCCC(C)C

nearest known ligand 0.65

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 1/20 0.65
ZDHHC2 Q9UIJ5 1/20 0.65
TSHR P16473 2/20 0.43
MAPK1 P28482 2/20 0.43
ALDH1A1 P00352 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
TGM2 P21980 12/20 0.43
GAA P10253 1/20 0.40
EPHX1 P07099 1/20 0.40
KDM4E B2RXH2 1/20 0.39
HIF1A Q16665 1/20 0.39
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL645427 1.00 ZDHHC20 (0.65) ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1
SCHEMBL7973204 1.00 ZDHHC20 (0.65) ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1
SCHEMBL20503668 1.00 ZDHHC20 (0.65) ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1
SCHEMBL20503696 1.00 ZDHHC20 (0.65) ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1
SCHEMBL20503620 1.00 ZDHHC20 (0.65) ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1
SCHEMBL20503608 1.00 ZDHHC20 (0.65) ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1
SCHEMBL20503659 1.00 ZDHHC20 (0.65) ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1
SCHEMBL20503580 1.00 ZDHHC20 (0.65) ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1
SCHEMBL20503561 1.00 ZDHHC20 (0.65) ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1
SCHEMBL9359066 1.00 ZDHHC20 (0.65) ZDHHC20ZDHHC2TSHRMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180333345-A1 NON-AQUEOUS COMPOSITIONS OF POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL MOIETY AND LACTAM MOIETY AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-11-22 US claimed
EP-3377547-A1 ON-AQUEOUS COMPOSITIONS OF POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL MOIETY AND LACTAM MOIETY AND APPLICATIONS THEREOF ISP Investments LLC (US) 2018-09-26 EP claimed
US-10632059-B2 Non-aqueous compositions of polymers derived from monomers having acryloyl moiety and lactam moiety and applications thereof ISP INVESTMENTS LLC (US) 2020-04-28 US disclosed
US-20180333345-A1 NON-AQUEOUS COMPOSITIONS OF POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL MOIETY AND LACTAM MOIETY AND APPLICATIONS THEREOF ISP INVESTMENTS LLC (US) 2018-11-22 US disclosed
EP-3377547-A1 ON-AQUEOUS COMPOSITIONS OF POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL MOIETY AND LACTAM MOIETY AND APPLICATIONS THEREOF ISP Investments LLC (US) 2018-09-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10632059-B2 Non-aqueous compositions of polymers derived from monomers having acryloyl moiety and lactam moiety and applications thereof C9, PARG, C5 ZDHHC20 1306/4885ZDHHC2 3290/4885TSHR 4135/4885
US-20180333345-A1 NON-AQUEOUS COMPOSITIONS OF POLYMERS DERIVED FROM MONOMERS HAVING ACRYLOYL MOIETY AND LACTAM MOIETY AND APPLICATIONS THEREOF C9, C5, C1S ZDHHC20 1566/4885ZDHHC2 3377/4885TSHR 4056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.