Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | SPIN1 | Q9Y657 | 1/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.47 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.47 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11383772 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10ALOX15KMT2A | |
| SCHEMBL19477129 | 0.80 | SPIN1 (0.54) | KDM4EALDH1A1HSD17B10ALOX15KMT2A | |
| SCHEMBL30474838 | 0.78 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10ALOX15KMT2A | |
| SCHEMBL6344529 | 0.76 | EHMT2 (0.52) | SPIN1 | |
| SCHEMBL23784378 | 0.75 | EHMT2 (0.51) | KDM4EALDH1A1HSD17B10ALOX15KMT2A | |
| SCHEMBL20504510 | 0.75 | EHMT2 (0.52) | SPIN1 | |
| SCHEMBL11816205 | 0.75 | KDM5A (0.47) | KDM4EALDH1A1HSD17B10ALOX15KMT2A | |
| SCHEMBL23784367 | 0.74 | EHMT2 (0.52) | KDM4EALDH1A1HSD17B10ALOX15KMT2A | |
| Formic Acid SCHEMBL20580538 | 0.73 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10ALOX15KMT2A | |
| SCHEMBL20304023 | 0.73 | EHMT2 (0.56) | KDM4EALDH1A1HSD17B10ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10407423-B2 | Compounds as inhibitors of DNA methyltransferases | FUNDACIÓN PARA LA INVESTIGACIÓN MÉDICA APLICADA (ES) | 2019-09-10 | — | — | US | disclosed |
| US-20180362525-A1 | NOVEL COMPOUNDS AS INHIBITORS OF DNA METHYLTRANSFERASES | FUNDACIÓN PARA LA INVESTIGACIÓN MÉDICA APLICADA (ES) | 2018-12-20 | — | — | US | disclosed |
| EP-3377490-A1 | NOVEL COMPOUNDS AS INHIBITORS OF DNA METHYLTRANSFERASES | Fundacion para la Investigacion Medica Aplicada (ES) | 2018-09-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180362525-A1 | NOVEL COMPOUNDS AS INHIBITORS OF DNA METHYLTRANSFERASES | DNMT3B, DNMT3A, DNMT1 | KDM4E 61/4885ALDH1A1 323/4885HSD17B10 2122/4885 |
| US-10407423-B2 | Compounds as inhibitors of DNA methyltransferases | DNMT3B, DNMT3A, DNMT1 | KDM4E 64/4885ALDH1A1 367/4885HSD17B10 2175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.