Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11383772 | 0.83 | KDM4E (0.57) | KDM5AKDM5BKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11818525 | 0.80 | KDM5A (0.52) | KDM5AKDM5BKDM4EALDH1A1LMNA | |
| SCHEMBL11814916 | 0.80 | KDM5A (0.52) | KDM5AKDM5BKDM4EALDH1A1LMNA | |
| SCHEMBL11817456 | 0.80 | KDM5A (0.55) | KDM5AKDM5BKDM4EALDH1A1LMNA | |
| SCHEMBL11818406 | 0.79 | ALDH1A1 (0.51) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL31422810 | 0.78 | KDM5A (0.57) | KDM5AKDM5BKDM4EALDH1A1LMNA | |
| SCHEMBL20504600 | 0.75 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10MAPK1HPGD | |
| SCHEMBL11821942 | 0.72 | NPSR1 (0.47) | KDM4EALDH1A1TP53MAPTKMT2A | |
| SCHEMBL11375801 | 0.71 | KMT2A (0.61) | KDM4EALDH1A1HSD17B10MAPK1HPGD | |
| SCHEMBL13312806 | 0.71 | KDM5A (0.59) | KDM5AKDM5BKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960868-A | Derivatives of 6,7 or 8 cycloalkyl 4-oxo quinoline 3 carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |