Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782348 | 0.83 | AKT1 (0.55) | AKT1CTSLCTSBCTSSRIPK1 | |
| SCHEMBL3424561 | 0.81 | TDP1 (0.50) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL782349 | 0.79 | AKT1 (0.51) | AKT1CTSLCTSBCTSSRIPK1 | |
| SCHEMBL7570965 | 0.78 | AKT1 (0.50) | AKT1CTSLCTSBCTSSRIPK1 | |
| SCHEMBL8018235 | 0.78 | AKT1 (0.50) | AKT1CTSLCTSBCTSSRIPK1 | |
| SCHEMBL23130693 | 0.78 | AKT1 (0.50) | AKT1CTSLCTSBCTSSRIPK1 | |
| SCHEMBL30915258 | 0.78 | AKT1 (0.50) | AKT1CTSLCTSBCTSSRIPK1 | |
| SCHEMBL20506779 | 0.77 | TDP1 (0.54) | CA12TRPM8CRHBPCRHR2 | |
| SCHEMBL7562431 | 0.77 | AKT1 (0.49) | AKT1CTSLCTSBCTSSRIPK1 | |
| SCHEMBL6086217 | 0.75 | AKT1 (0.45) | AKT1CTSLCTSBCTSSRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11420910-B2 | Methods for low temperature fluorine-18 radiolabeling of biomolecules | KATHOLIEKE UNIVERSITET LEUVEN (BE) | 2022-08-23 | — | — | US | disclosed |
| EP-3212610-B1 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | UNIV LEUVEN KATH (BE) | 2020-10-28 | — | — | EP | disclosed |
| US-20180273441-A1 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180273441-A1 | METHODS FOR LOW TEMPERATURE FLUORINE-18 RADIOLABELING OF BIOMOLECULES | H1-3, H1-0, H1-2 | AKT1 4264/4885CTSL 548/4885CTSB 2192/4885 |
| US-11420910-B2 | Methods for low temperature fluorine-18 radiolabeling of biomolecules | H1-3, H1-0, H1-2 | AKT1 4254/4885CTSL 548/4885CTSB 2223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.