Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.51 |
| ▸ | NR1D1 | P20393 | 4/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL782348 | 0.95 | AKT1 (0.55) | AKT1NR1D1CTSLCTSBCTSS | |
| SCHEMBL23130693 | 0.89 | AKT1 (0.50) | AKT1NR1D1CTSLCTSBCTSS | |
| SCHEMBL7570965 | 0.89 | AKT1 (0.50) | AKT1NR1D1CTSLCTSBCTSS | |
| SCHEMBL8018235 | 0.89 | AKT1 (0.50) | AKT1NR1D1CTSLCTSBCTSS | |
| SCHEMBL30915258 | 0.89 | AKT1 (0.50) | AKT1NR1D1CTSLCTSBCTSS | |
| SCHEMBL7562431 | 0.88 | AKT1 (0.49) | AKT1NR1D1CTSLCTSBCTSS | |
| SCHEMBL3844227 | 0.87 | MEN1 (0.52) | AKT1NR1D1CTSLCTSBCTSS | |
| SCHEMBL3775112 | 0.87 | AKT1 (0.51) | AKT1NR1D1CTSLCTSBCTSS | |
| SCHEMBL25539127 | 0.87 | AKT1 (0.48) | AKT1NR1D1CTSLCTSBCTSS | |
| SCHEMBL13163615 | 0.85 | TSHR (0.53) | AKT1NR1D1CTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070856-A1 | CROSS-LINKING AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070856-A1 | CROSS-LINKING AGENTS | ORC3, TXN, PROC | AKT1 4739/4885NR1D1 2177/4885CTSL 4328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.