Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ITK | Q08881 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801536 | 0.82 | RAB9A (0.49) | AURKAAURKBRAB9ANPC1ESR1 | |
| SCHEMBL20508265 | 0.82 | HPGD (0.60) | AURKAAURKBRAB9ANPC1KDM4E | |
| SCHEMBL21801476 | 0.81 | GSK3B (0.48) | AURKAAURKBRAB9ANPC1ESR1 | |
| SCHEMBL20508264 | 0.81 | NPC1 (0.61) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL9390542 | 0.80 | RAB9A (0.44) | AURKAAURKBRAB9ANPC1ESR1 | |
| SCHEMBL20508257 | 0.80 | GUSB (0.48) | AURKAAURKBRAB9ANPC1ESR1 | |
| SCHEMBL20508324 | 0.80 | RAB9A (0.44) | AURKAAURKBRAB9ANPC1ESR1 | |
| SCHEMBL20508267 | 0.80 | RAB9A (0.44) | AURKAAURKBRAB9ANPC1ESR1 | |
| SCHEMBL20508319 | 0.78 | NPC1 (0.57) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL20508314 | 0.77 | RAB9A (0.44) | AURKAAURKBRAB9ANPC1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11026426-B2 | Oxadiazole and phenol derivatives as antibacterial and/or herbicidal agents | NORTHERN ILLINOIS RESEARCH FOUNDATION (US) | 2021-06-08 | — | — | US | disclosed |
| US-11026426-B2 | Oxadiazole and phenol derivatives as antibacterial and/or herbicidal agents | NORTHERN ILLINOIS RESEARCH FOUNDATION (US) | 2021-06-08 | — | — | US | disclosed |
| US-20180271098-A1 | OXADIAZOLE AND PHENOL DERIVATIVES AS ANTIBACTERIAL AND/OR HERBICIDAL AGENTS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180271098-A1 | OXADIAZOLE AND PHENOL DERIVATIVES AS ANTIBACTERIAL AND/OR HERBICIDAL AGENTS | CMPK1, IPMK, ITPA | AURKA 867/4885AURKB 833/4885RAB9A 4196/4885 |
| US-11026426-B2 | Oxadiazole and phenol derivatives as antibacterial and/or herbicidal agents | CBR3, AOC3, AHR | AURKA 1622/4885AURKB 1721/4885RAB9A 4222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.