Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31315989 | 1.00 | ALDH1A1 (0.67) | ALDH1A1MAPTSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL31315992 | 0.83 | ALDH1A1 (0.72) | ALDH1A1MAPTSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL20508328 | 0.83 | ALDH1A1 (0.72) | ALDH1A1MAPTSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL17962933 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPTSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL31315988 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPTSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL169905 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL29729259 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL17962931 | 0.75 | TRPV1 (0.68) | ALDH1A1MAPTSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL20508332 | 0.75 | TRPV1 (0.63) | ALDH1A1MAPTSMN1; SMN2MEN1CYP3A4 | |
| SCHEMBL20508304 | 0.74 | ALDH1A1 (0.61) | ALDH1A1MAPTSMN1; SMN2MEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3250551-B1 | ANTI-CANCER COMPOUNDS | UNIV SYDNEY (AU) | 2022-11-09 | — | — | EP | disclosed |
| US-10745355-B2 | Anti-cancer compounds | THE UNIVERSITY OF SYDNEY (AU) | 2020-08-18 | — | — | US | disclosed |
| US-10745355-B2 | Anti-cancer compounds | THE UNIVERSITY OF SYDNEY (AU) | 2020-08-18 | — | — | US | disclosed |
| US-20180273478-A1 | ANTI-CANCER COMPOUNDS | THE UNIVERSITY OF SYDNEY (AU) | 2018-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180273478-A1 | ANTI-CANCER COMPOUNDS | MKI67, TP53, CDK5 | ALDH1A1 1509/4885MAPT 342/4885SMN1; SMN2 1105/4885 |
| US-10745355-B2 | Anti-cancer compounds | MKI67, TP53, CDK5 | ALDH1A1 1509/4885MAPT 342/4885SMN1; SMN2 1105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.