Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 7/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 4/20 | 0.45 |
| ▸ | ABCC2 | Q92887 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.45 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | ABCC5 | O15440 | 1/20 | 0.45 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4957634 | 0.84 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL32665692 | 0.82 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL28025551 | 0.81 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL4961219 | 0.81 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL13985849 | 0.81 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL3228018 | 0.81 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL4416693 | 0.80 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL4416695 | 0.80 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL14843663 | 0.79 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 | |
| SCHEMBL14843664 | 0.79 | CYSLTR1 (0.55) | CYSLTR1CYSLTR2ABCC1ABCC2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008035379-A2 | PROCESS FOR AND INTERMEDIATES OF LEUKOTRIENE ANTAGONISTS | APTUIT LAURUS PRIVATE LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2009001374-A3 | PREPARATION OF ETHYL-3'-[((7-CHLORO-2-QUINOLINYL)ETHENYL)PHENYL]-3-OXOPROPANOATE, A KEY INTERMEDIATE FOR MONTELUKAST SODIUM | APTUIT LAURUS PVT LTD (IN) | 2011-06-30 | — | — | WO | disclosed |
| WO-2008035379-A3 | PROCESS FOR AND INTERMEDIATES OF LEUKOTRIENE ANTAGONISTS | APTUIT LAURUS PRIVATE LIMITED (IN) | 2010-02-18 | — | — | WO | disclosed |
| WO-2009001374-A2 | PREPARATION OF ETHYL-3'-[((7-CHLORO-2-QUINOLINYL)ETHENYL)PHENYL]-3-OXOPROPANOATE, A KEY INTERMEDIATE FOR MONTELUKAST SODIUM | APTUIT LAURUS PVT LTD (IN) | 2008-12-31 | — | — | WO | disclosed |
| WO-2008035379-A2 | PROCESS FOR AND INTERMEDIATES OF LEUKOTRIENE ANTAGONISTS | APTUIT LAURUS PRIVATE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |
| WO-2008035379-A2 | PROCESS FOR AND INTERMEDIATES OF LEUKOTRIENE ANTAGONISTS | APTUIT LAURUS PRIVATE LIMITED (IN) | 2008-03-27 | — | — | WO | disclosed |