Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.36 |
| ▸ | ALB | P02768 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 6/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13812218 | 0.86 | FGFR1 (0.57) | FGFR1LMNAPDE3ACACNA1FALB | |
| SCHEMBL27292735 | 0.84 | FGFR1 (0.69) | FGFR1LMNAPDE3ACACNA1FALB | |
| SCHEMBL20509969 | 0.75 | FGFR1 (0.59) | FGFR1LMNAPDE3ACACNA1FALB | |
| Cyclic Cidofovir SCHEMBL14461986 | 0.74 | FGFR1 (1.00) | FGFR1LMNAPDE3ACACNA1FALB | |
| Cyclic Cidofovir SCHEMBL140858 | 0.74 | FGFR1 (1.00) | FGFR1LMNAPDE3ACACNA1FALB | |
| Cyclic Cidofovir SCHEMBL2380283 | 0.74 | FGFR1 (1.00) | FGFR1LMNAPDE3ACACNA1FALB | |
| Glycidol SCHEMBL543441 | 0.72 | FGFR1 (0.55) | FGFR1LMNAPDE3ACACNA1FALB | |
| SCHEMBL8925507 | 0.72 | FGFR1 (0.55) | FGFR1LMNAPDE3ACACNA1FALB | |
| SCHEMBL10047653 | 0.72 | FGFR1 (0.74) | FGFR1LMNAPDE3ACACNA1FALB | |
| SCHEMBL10047660 | 0.71 | FGFR1 (0.69) | FGFR1LMNAPDE3ACACNA1FALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3600556-A1 | NOVEL PRODRUGS OF NUCLEOSIDE PHOSPHONATES | Katholieke Universiteit Leuven (BE) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018172416-A1 | NOVEL PRODRUGS OF NUCLEOSIDE PHOSPHONATES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-09-27 | — | — | WO | disclosed |