Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.33 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18653856 | 1.00 | FOLH1 (0.38) | FOLH1IDO1CHRM1TBXA2RADRA1A | |
| SCHEMBL18653858 | 0.88 | CHRM1 (0.33) | FOLH1CHRM1TBXA2RADRA1AALDH1A1 | |
| SCHEMBL18631761 | 0.80 | PSMB11 (0.35) | FOLH1CHRM1TBXA2RADRA1AMAPT | |
| SCHEMBL18650384 | 0.80 | TYR (0.37) | FOLH1CHRM1TBXA2RADRA1A | |
| SCHEMBL20510688 | 0.80 | PSMB11 (0.35) | FOLH1CHRM1TBXA2RADRA1AMAPT | |
| SCHEMBL18650397 | 0.80 | PSMB11 (0.35) | FOLH1CHRM1TBXA2RADRA1AMAPT | |
| SCHEMBL18653855 | 0.79 | IDO1 (0.41) | IDO1KIF11KLKB1 | |
| SCHEMBL22939353 | 0.79 | FOLH1 (0.33) | FOLH1CHRM1TBXA2RADRA1A | |
| SCHEMBL18660439 | 0.78 | FOLH1 (0.33) | FOLH1IDO1CHRM1TBXA2RADRA1A | |
| SCHEMBL17509691 | 0.77 | FOLH1 (0.41) | FOLH1CHRM1TBXA2RADRA1AGRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018174839-A1 | CYSTEINE, N-ACETYLCYSTEINE AND PENICILLAMINE PRODRUGS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | NGUYEN MARK QUANG (US) | 2018-09-27 | — | — | WO | disclosed |