Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.35 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.35 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.35 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.35 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.35 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.35 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.35 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.35 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.35 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.35 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.35 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.35 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.35 |
| ▸ | SF3B3 | Q15393 | 1/20 | 0.35 |
| ▸ | PSMA8 | Q8TAA3 | 1/20 | 0.35 |
| ▸ | PSMB7 | Q99436 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18650397 | 1.00 | PSMB11 (0.35) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL18631761 | 1.00 | PSMB11 (0.35) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL18631756 | 0.91 | TYR (0.37) | FOLH1CHRM1TBXA2RADRA1APPARG | |
| SCHEMBL18650384 | 0.91 | TYR (0.37) | FOLH1CHRM1TBXA2RADRA1APPARG | |
| SCHEMBL18650403 | 0.89 | TACR1 (0.33) | FOLH1TACR1 | |
| SCHEMBL18653810 | 0.87 | KDM4E (0.37) | FOLH1MAPTKDM4EALDH1A1RXFP1 | |
| SCHEMBL20122450 | 0.85 | ACE (0.37) | FOLH1CHRM1TBXA2RADRA1A | |
| SCHEMBL20122425 | 0.85 | FOLH1 (0.32) | FOLH1CHRM1TBXA2RADRA1A | |
| SCHEMBL18653811 | 0.84 | PAM (0.38) | PSMB11PSMA7PSMB1PSMA1PSMA2 | |
| SCHEMBL20510285 | 0.80 | FOLH1 (0.38) | FOLH1MAPTALOX15BLMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018174839-A1 | CYSTEINE, N-ACETYLCYSTEINE AND PENICILLAMINE PRODRUGS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | NGUYEN MARK QUANG (US) | 2018-09-27 | — | — | WO | disclosed |