Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.43 |
| ▸ | PPARG | P37231 | 12/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2051102 | 1.00 | PPARA (0.43) | PPARAPPARGLMNAMAPK1HTT | |
| SCHEMBL2050607 | 0.92 | PPARA (0.44) | PPARAPPARGLMNAMAPK1HTT | |
| SCHEMBL2050606 | 0.92 | PPARA (0.44) | PPARAPPARGLMNAMAPK1HTT | |
| SCHEMBL2047973 | 0.88 | PPARA (0.41) | PPARAPPARGLMNAMAPK1HTT | |
| SCHEMBL2047974 | 0.88 | PPARA (0.41) | PPARAPPARGLMNAMAPK1HTT | |
| SCHEMBL2043135 | 0.85 | HTT (0.40) | PPARAPPARGLMNAMAPK1HTT | |
| SCHEMBL2043136 | 0.85 | HTT (0.40) | PPARAPPARGLMNAMAPK1HTT | |
| SCHEMBL2047076 | 0.85 | PPARA (0.42) | PPARAPPARGLMNAMAPK1HTT | |
| SCHEMBL2047077 | 0.85 | PPARA (0.42) | PPARAPPARGLMNAMAPK1HTT | |
| SCHEMBL9899218 | 0.83 | NR4A2 (0.49) | PPARAPPARGLMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2516475-B1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORP (JP) | 2020-10-07 | — | — | EP | claimed |
| US-8338544-B2 | Polymers functionalized with polyoxime compounds and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2012-12-25 | — | — | US | claimed |
| US-20110152449-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | claimed |
| EP-2516475-B1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORP (JP) | 2020-10-07 | — | — | EP | disclosed |
| US-8338544-B2 | Polymers functionalized with polyoxime compounds and methods for their manufacture | BRIDGESTONE CORPORATION (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20110152449-A1 | POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE | BRIDGESTONE CORPORATION (JP) | 2011-06-23 | — | — | US | disclosed |