SCHEMBL2050607

SCHEMBL2050607

C[Si](C)(C)ON=C(CCC(=NO[Si](C)(C)C)c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 10/20 0.44
ATM Q13315 1/20 0.44
LMNA P02545 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PPARG P37231 10/20 0.40
DRD4 P21917 6/20 0.38
DRD2 P14416 2/20 0.38
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2050606 1.00 PPARA (0.44) PPARAATMLMNAMAPK1HTT
SCHEMBL2047076 0.93 PPARA (0.42) PPARAATMLMNAMAPK1HTT
SCHEMBL2047077 0.93 PPARA (0.42) PPARAATMLMNAMAPK1HTT
SCHEMBL2051102 0.92 PPARA (0.43) PPARAATMLMNAMAPK1HTT
SCHEMBL2051100 0.92 PPARA (0.43) PPARAATMLMNAMAPK1HTT
SCHEMBL9899218 0.90 NR4A2 (0.49) PPARALMNAMAPK1HTTL3MBTL1
SCHEMBL9899246 0.90 NR4A2 (0.49) PPARALMNAMAPK1HTTL3MBTL1
SCHEMBL9897845 0.84 L3MBTL1 (0.50) PPARALMNAL3MBTL1GAA
SCHEMBL9897843 0.84 L3MBTL1 (0.50) PPARALMNAL3MBTL1GAA
SCHEMBL2045904 0.84 ATM (0.40) PPARAATMLMNAMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516475-B1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2020-10-07 EP claimed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US claimed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP claimed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US claimed
EP-2516475-B1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2020-10-07 EP disclosed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US disclosed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP disclosed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed