Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Di(Hydroxyethyl)Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Di(Hydroxyethyl)Ether SCHEMBL55330 | 0.94 | TSHR (0.56) | SMN1; SMN2ALDH1A1TSHRTDP1MAPK1 | |
| Tetraethylene Glycol SCHEMBL55602 | 0.91 | TSHR (0.54) | SMN1; SMN2ALDH1A1TSHRTDP1MAPK1 | |
| Triethylene Glycol SCHEMBL17007808 | 0.91 | TSHR (0.54) | SMN1; SMN2ALDH1A1TSHRTDP1MAPK1 | |
| Triethylene Glycol SCHEMBL54012 | 0.91 | TSHR (0.54) | SMN1; SMN2ALDH1A1TSHRTDP1MAPK1 | |
| Di(Hydroxyethyl)Ether SCHEMBL28146417 | 0.91 | TSHR (0.54) | SMN1; SMN2ALDH1A1TSHRTDP1MAPK1 | |
| Triethylene Glycol SCHEMBL27622048 | 0.90 | TSHR (0.48) | SMN1; SMN2ALDH1A1TSHRTDP1MAPK1 | |
| Di(Hydroxyethyl)Ether SCHEMBL1477230 | 0.90 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1TSHRTDP1MAPK1 | |
| Alcohol SCHEMBL150777 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1TSHRTDP1MAPK1 | |
| SCHEMBL28572989 | 0.88 | TSHR (0.47) | SMN1; SMN2ALDH1A1TSHRTDP1MAPK1 | |
| Tetraethylene Glycol SCHEMBL16005000 | 0.88 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1TSHRTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381972-B1 | SUPERABSORBENT POLYMER AND THE METHOD OF FABRICATING THE SAME | FORMOSA PLASTICS CORP (TW) | 2021-07-07 | — | — | EP | disclosed |
| US-10731024-B2 | Superabsorbent polymer and the method of fabricating the same | FORMOSA PLASTICS CORPORATION (TW) | 2020-08-04 | — | — | US | disclosed |
| US-10550243-B2 | Superabsorbent polymer and the method of fabricating the same | FORMOSA PLASTICS CORPORATION (TW) | 2020-02-04 | — | — | US | disclosed |
| US-20180282507-A1 | SUPERABSORBENT POLYMER AND THE METHOD OF FABRICATING THE SAME | FORMOSA PLASTICS CORPORATION (TW) | 2018-10-04 | — | — | US | disclosed |
| US-20180282515-A1 | SUPERABSORBENT POLYMER AND THE METHOD OF FABRICATING THE SAME | FORMOSA PLASTICS CORPORATION (TW) | 2018-10-04 | — | — | US | disclosed |
| EP-3381970-A1 | SUPERABSORBENT POLYMER AND THE METHOD OF FABRICATING THE SAME | Formosa Plastics Corporation (TW) | 2018-10-03 | — | — | EP | disclosed |
| EP-3381972-A1 | SUPERABSORBENT POLYMER AND THE METHOD OF FABRICATING THE SAME | Formosa Plastics Corporation (TW) | 2018-10-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10550243-B2 | Superabsorbent polymer and the method of fabricating the same | STOM, SAP18, PCNA | SMN1; SMN2 4559/4885ALDH1A1 2316/4885TSHR 4000/4885 |
| US-20180282515-A1 | SUPERABSORBENT POLYMER AND THE METHOD OF FABRICATING THE SAME | STOM, SAP18, PCNA | SMN1; SMN2 4559/4885ALDH1A1 2316/4885TSHR 4000/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.