Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | BRD4 | O60885 | 1/20 | 0.60 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.58 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.58 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.50 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10641093 | 0.83 | BRD4 (0.65) | POLBMEN1KMT2AMAPK1BRD4 | |
| SCHEMBL9458368 | 0.82 | HSD17B10 (0.76) | POLBMEN1KMT2AMAPK1BRD4 | |
| SCHEMBL20346175 | 0.82 | BRD4 (0.63) | POLBMEN1KMT2AMAPK1BRD4 | |
| SCHEMBL9803534 | 0.81 | LPAR1 (0.77) | POLBMEN1KMT2AMAPK1BRD4 | |
| SCHEMBL6720226 | 0.80 | BRD4 (0.58) | POLBMEN1KMT2AMAPK1BRD4 | |
| SCHEMBL261725 | 0.80 | BRD4 (0.68) | POLBMEN1KMT2AMAPK1BRD4 | |
| SCHEMBL19689370 | 0.79 | BRD4 (0.72) | POLBMEN1KMT2AMAPK1BRD4 | |
| SCHEMBL24149295 | 0.79 | MEN1 (0.74) | POLBMEN1KMT2AMAPK1BRD4 | |
| SCHEMBL20081072 | 0.79 | BRD4 (0.60) | POLBMEN1KMT2AMAPK1BRD4 | |
| SCHEMBL29393214 | 0.78 | POLB (0.67) | POLBMAPK1ALDH1A1HPSETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3381906-A1 | COMPOUNDS FOR USE AS HEPARANASE INHIBITORS | Leadiant Biosciences SA (CH) | 2018-10-03 | — | — | EP | claimed |