Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.47 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17272758 | 0.85 | BRD4 (0.73) | BRD4KMT2AMEN1HTTPOLB | |
| SCHEMBL19322288 | 0.84 | PTGES (0.61) | BRD4KMT2AMEN1POLBMAPK1 | |
| SCHEMBL20081123 | 0.82 | BRD4 (0.86) | BRD4KMT2AMEN1HTTPOLB | |
| SCHEMBL261725 | 0.80 | BRD4 (0.68) | BRD4KMT2AMEN1HTTPOLB | |
| SCHEMBL13678848 | 0.79 | MEN1 (0.69) | BRD4KMT2AMEN1HTTPOLB | |
| SCHEMBL19689370 | 0.79 | BRD4 (0.72) | BRD4KMT2AMEN1HTTPOLB | |
| SCHEMBL12289346 | 0.79 | MAPK1 (0.48) | BRD4KMT2AMEN1HTTPOLB | |
| SCHEMBL20512982 | 0.79 | POLB (0.63) | BRD4KMT2AMEN1POLBMAPK1 | |
| SCHEMBL17281694 | 0.78 | PTGES (0.64) | BRD4KMT2AMEN1POLBMAPK1 | |
| SCHEMBL10000442 | 0.78 | BRD4 (0.74) | BRD4KMT2AMEN1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145974-B1 | METHOD FOR MAKING PARTICULATE AMINE-FUNCTIONALIZED POLYARYLETHERKETONE POLYMERS AND COPOLYMERS THEREOF | KETONEX LTD (GB) | 2018-04-25 | — | — | EP | disclosed |