SCHEMBL2051802

SCHEMBL2051802

CCCC(=N\OS(=O)(=O)c1ccccc1)/C(C)=N/OS(=O)(=O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.43
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 3/20 0.42
KMT2A Q03164 2/20 0.42
MAPK1 P28482 2/20 0.41
XBP1 P17861 4/20 0.38
MPI P34949 4/20 0.38
NPSR1 Q6W5P4 4/20 0.38
HSP90AA1 P07900 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
HSD11B1 P28845 1/20 0.37
PSIP1 O75475 1/20 0.37
S1PR2 O95136 3/20 0.37
LMNA P02545 3/20 0.37
RAB9A P51151 3/20 0.37
PKM P14618 2/20 0.37
HTT P42858 2/20 0.37
OPRM1 P35372 1/20 0.37
OPRD1 P41143 1/20 0.37
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2051803 1.00 MAPT (0.43) MAPTALDH1A1KDM4EKMT2AMAPK1
SCHEMBL2050095 0.88 MAPT (0.44) MAPTALDH1A1KDM4EKMT2AMAPK1
SCHEMBL2050096 0.88 MAPT (0.44) MAPTALDH1A1KDM4EKMT2AMAPK1
SCHEMBL9898046 0.85 MAPK1 (0.44) MAPTALDH1A1KDM4EKMT2AMAPK1
SCHEMBL9898048 0.85 MAPK1 (0.44) MAPTALDH1A1KDM4EKMT2AMAPK1
SCHEMBL212157 0.83 MAPT (0.51) MAPTALDH1A1KDM4EKMT2AMAPK1
SCHEMBL212158 0.83 MAPT (0.51) MAPTALDH1A1KDM4EKMT2AMAPK1
SCHEMBL2048635 0.82 MAPT (0.53) MAPTALDH1A1KDM4EKMT2AMAPK1
SCHEMBL2048632 0.82 MAPT (0.53) MAPTALDH1A1KDM4EKMT2AMAPK1
SCHEMBL213417 0.81 MAPT (0.47) MAPTALDH1A1KDM4EKMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US claimed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP claimed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US claimed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US disclosed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed