SCHEMBL205186

SCHEMBL205186

O=c1cc(CCl)c2ccc(O)cc2o1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B3 P37058 12/20 0.73
AKR1B1 P15121 2/20 0.68
LCK P06239 1/20 0.68
FYN P06241 1/20 0.68
GRB2 P62993 1/20 0.68
MCL1 Q07820 3/20 0.66
ALDH1A1 P00352 4/20 0.64
GAA P10253 3/20 0.64
ERAP1 Q9NZ08 1/20 0.64
KDM4E B2RXH2 3/20 0.62
KMT2A Q03164 1/20 0.62
GLA P06280 2/20 0.61
CA12 O43570 1/20 0.58
LMNA P02545 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2C9 P11712 1/20 0.58
HPGD P15428 1/20 0.58
UGT1A1 P22309 1/20 0.58
MAOB P27338 1/20 0.58
CASP1 P29466 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28294964 1.00 HSD17B3 (0.73) HSD17B3AKR1B1LCKFYNGRB2
SCHEMBL30185458 1.00 HSD17B3 (0.73) HSD17B3AKR1B1LCKFYNGRB2
SCHEMBL15245387 0.87 MCL1 (0.66) HSD17B3AKR1B1LCKFYNGRB2
SCHEMBL3762732 0.85 HSD17B3 (1.00) HSD17B3AKR1B1LCKFYNGRB2
SCHEMBL4176874 0.85 HSD17B3 (0.76) HSD17B3AKR1B1LCKFYNGRB2
SCHEMBL1252272 0.83 HSD17B3 (0.73) HSD17B3AKR1B1LCKFYNGRB2
SCHEMBL3868315 0.83 HSD17B3 (0.73) HSD17B3AKR1B1LCKFYNGRB2
SCHEMBL27989780 0.83 HSD17B3 (0.73) HSD17B3AKR1B1LCKFYNGRB2
SCHEMBL7738289 0.83 HSD17B3 (0.77) HSD17B3AKR1B1LCKFYNGRB2
SCHEMBL27757150 0.83 HSD17B3 (0.73) HSD17B3AKR1B1LCKFYNGRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114671912-B Method for homogeneously synthesizing blue copper tripeptide with assistance of light shearing carrier 西北工业大学 2024-05-14 CN claimed
CN-115612140-B Preparation method of fluorescent waterborne polyurethane film for organic amine detection 潍坊弘润新材料有限公司 2023-03-28 CN claimed
CN-115612140-A Preparation method of fluorescent waterborne polyurethane film for organic amine detection 潍坊弘润新材料有限公司 2023-01-17 CN claimed
CN-107089963-B With inhibition active cumarin esterification derivative of RXR alpha transcriptional and its preparation method and application 厦门大学 2019-05-21 CN claimed
WO-2018203315-A1 METHOD FOR MICROORGANISM EXTRACTION AND/OR FOR DETERMINATION OF A MICROORGANISM MAIN RESISTANCE MECHANISM AND/OR THE MINIMUM INHIBITORY CONCENTRATION OF A THERAPEUTICAL AGENT, KITS AND USES THEREOF UNIVERSIDADE DO PORTO (PT) 2018-11-08 WO claimed
EP-2820147-B1 RAPID ANTIBIOTIC SUSCEPTIBILITY TESTING HARVARD COLLEGE (US) 2018-08-08 EP claimed
CN-104284984-B Rapid antibiotic susceptibility testing 哈佛大学校长及研究员协会 2017-10-13 CN claimed
CN-107089963-A With cumarin esterification derivative for suppressing RXR alpha transcriptionals activity and its preparation method and application 厦门大学 2017-08-25 CN claimed
US-9632085-B2 Rapid antibiotic susceptibility testing PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2017-04-25 US claimed
CN-103570701-B A kind of coumarin derivatives and its preparation method and application SHANXI UNIVERISTY (CN) 2015-09-30 CN claimed
CN-103570701-A Coumarin derivatives as well as preparation method and application thereof UNIV SHANXI 2014-02-12 CN claimed
WO-2013130875-A1 RAPID ANTIBIOTIC SUSCEPTIBILITY TESTING PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2013-09-06 WO claimed
CN-102924417-A 4-(chloromethyl)-7-hydroxy coumarin compound and preparation method thereof TIANJIN HEOWNS BIOCHEMISTRY TECHNOLOGY CO LTD 2013-02-13 CN claimed
CN-1996015-A Flow cytometry biochip for use in immune monitoring and research and development of medicine LIN YUAN (CN) 2007-07-11 CN claimed
CN-1970788-A Flow cytometry and intracellular molecular probe technology ZHENG FANG (CN) 2007-05-30 CN claimed
EP-0731664-B1 SENSOR WITH IMPROVED DRIFT STABILITY TERUMO CARDIOVASCULAR SYS (US) 2002-02-27 EP claimed
US-5607645-A Sensor with improved drift stability MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-03-04 US claimed
EP-0731664-A1 SENSOR WITH IMPROVED DRIFT STABILITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-09-18 EP claimed
WO-1995015114-A1 SENSOR WITH IMPROVED DRIFT STABILITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-06-08 WO claimed
US-5403746-A Aqueous first phase comprising pH sensitive indicator in buffer solution dispersed in hydrophobic second phase permeable to analyte and impermeable to ionized hydrogen MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-04-04 US claimed