Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 14/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.75 |
| ▸ | GAA | P10253 | 3/20 | 0.75 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.75 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.69 |
| ▸ | LCK | P06239 | 1/20 | 0.69 |
| ▸ | FYN | P06241 | 1/20 | 0.69 |
| ▸ | GRB2 | P62993 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | GLA | P06280 | 2/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 1/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.65 |
| ▸ | CASP7 | P55210 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL536846 | 0.89 | HSD17B3 (1.00) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL24023252 | 0.86 | HSD17B3 (0.76) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL4176874 | 0.86 | HSD17B3 (0.76) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL10792047 | 0.86 | HSD17B3 (0.76) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL5138108 | 0.85 | HSD17B3 (1.00) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL10850530 | 0.85 | HSD17B3 (0.72) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL205186 | 0.85 | HSD17B3 (0.73) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL3868315 | 0.85 | HSD17B3 (0.73) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL7738289 | 0.85 | HSD17B3 (0.77) | HSD17B3ALDH1A1GAAERAP1AKR1B1 | |
| SCHEMBL30185458 | 0.85 | HSD17B3 (0.73) | HSD17B3ALDH1A1GAAERAP1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022258005-A1 | A PHOTORESPONSIVE DELIVERY SYSTEM BASED ON A MODIFIED PAMAM AND METHODS THEREOF | THE UNIVERSITY OF HONG KONG (CN) | 2022-12-15 | — | — | WO | disclosed |
| CN-110204535-B | Coumarin hydrazine hydrate fluorescent probe and preparation method thereof | 福州大学 | 2022-09-13 | — | — | CN | disclosed |
| US-10457619-B2 | Resorcinol derivatives for cosmetic use thereof | L'OREAL (FR) | 2019-10-29 | — | — | US | disclosed |
| CN-110204535-A | A kind of Coumarins hydrazine hydrate fluorescence probe and preparation method thereof | 福州大学 | 2019-09-06 | — | — | CN | disclosed |
| EP-3039009-B1 | MAO-B SELECTIVE INHIBITOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF AND USES THEREOF | UNIV BRITISH COLUMBIA (CA) | 2019-05-01 | — | — | EP | disclosed |
| US-9878046-B2 | Adverse side-effects associated with administration of an anti-hyaluronan agent and methods for ameliorating or preventing the side-effects | HALOZYME, INC. (US) | 2018-01-30 | — | — | US | disclosed |
| WO-2017102536-A1 | RESORCINOL DERIVATIVES FOR COSMETIC USE THEREOF | L'OREAL (FR) | 2017-06-22 | — | — | WO | disclosed |
| WO-2017102802-A1 | RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE | L'OREAL (FR) | 2017-06-22 | — | — | WO | disclosed |
| WO-2017102802-A1 | RESORCINOL DERIVATIVES FOR THEIR COSMETIC USE | L'OREAL (FR) | 2017-06-22 | — | — | WO | disclosed |
| CN-106470977-A | Water solublity can anakmetomeres probe, its synthetic intermediate and related detecting method | 里昂高等师范学院 | 2017-03-01 | — | — | CN | disclosed |
| WO-1996039021-A1 | FbLATE PROMOTER | THE MONSANTO COMPANY (US) | 1996-12-12 | — | — | WO | disclosed |
| CN-1027268-C | Process for preparing benzopyrone-beta-D-thioxylosides | FOURNIER IND & SANTE (FR) | 1995-01-04 | — | — | CN | disclosed |
| EP-0421829-B1 | Benzopyranone-beta-D-thioxylosides, method for their preparation and their use | FOURNIER IND & SANTE (FR) | 1994-11-09 | — | — | EP | disclosed |
| US-5169838-A | Anticoagulants | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-12-08 | — | — | US | disclosed |
| EP-0421829-A1 | Benzopyranone-beta-D-thioxylosides, method for their preparation and their use | FOURNIER INDUSTRIE ET SANTE (FR) | 1991-04-10 | — | — | EP | disclosed |
| CN-1050544-A | Novel benzopyrone-β-D-sulfo-xyloside, their preparation method and the application in treatment thereof | FOURNIER IND & SANTE (FR) | 1991-04-10 | — | — | CN | disclosed |
| EP-0111746-B1 | SULFONIC-ACID ESTERS OF HYDROXYCOUMARINES, THEIR PREPARATION AND MEDICINES CONTAINING THEM | BASF Aktiengesellschaft (DE) | 1987-09-16 | — | — | EP | disclosed |
| US-4618622-A | ANTIDEPRESSANTS, ANTIALLERGENS | BASF AKTIENGESELLSCHAFT (DE) | 1986-10-21 | — | — | US | disclosed |
| EP-0111746-A2 | Sulfonic-acid esters of hydroxycoumarines, their preparation and medicines containing them | BASF Aktiengesellschaft (DE) | 1984-06-27 | — | — | EP | disclosed |
| US-4298614-A | 5'-Aminoalkyl-4',4-dialkylpsoralens | THOMAS C. ELDER, INC. (US) | 1981-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10457619-B2 | Resorcinol derivatives for cosmetic use thereof | CBR3, C1S, TYR | HSD17B3 185/4885ALDH1A1 476/4885GAA 1478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.