SCHEMBL2051864

SCHEMBL2051864

c1ccc([Si](ON=C2CCCC(=NO[Si](c3ccccc3)(c3ccccc3)c3ccccc3)C2)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2051863 1.00 GAA (0.33) GAARAB9ASMN1; SMN2
SCHEMBL214990 0.89 GAA (0.41) GAARAB9ASMN1; SMN2
SCHEMBL9898028 0.89 MEN1 (0.38) GAARAB9ASMN1; SMN2
SCHEMBL9898026 0.89 MEN1 (0.38) GAARAB9ASMN1; SMN2
SCHEMBL212164 0.87 GAA (0.40) GAARAB9ASMN1; SMN2
SCHEMBL2044914 0.84 GAA (0.33) GAARAB9ASMN1; SMN2
SCHEMBL9897382 0.80 CYP1A2 (0.39)
SCHEMBL9897380 0.80 CYP1A2 (0.39)
SCHEMBL2052163 0.77 MAPT (0.32) GAA
SCHEMBL2052161 0.77 MAPT (0.32) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516475-B1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2020-10-07 EP claimed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US claimed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP claimed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US claimed
EP-2516475-B1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2020-10-07 EP disclosed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US disclosed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP disclosed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed