SCHEMBL2052161

SCHEMBL2052161

CC1(C)C/C(=N/O[Si](c2ccccc2)(c2ccccc2)c2ccccc2)C/C(=N/O[Si](c2ccccc2)(c2ccccc2)c2ccccc2)C1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.32
GAA P10253 2/20 0.32
KMT2A Q03164 4/20 0.31
MEN1 O00255 3/20 0.31
MAPK1 P28482 1/20 0.31
ALDH1A1 P00352 3/20 0.31
ATM Q13315 1/20 0.31
LMNA P02545 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2052163 1.00 MAPT (0.32) MAPTGAAKMT2AMEN1MAPK1
SCHEMBL9898839 0.90 GAA (0.44) MAPTGAAKMT2AMEN1ALDH1A1
SCHEMBL9898838 0.90 GAA (0.44) MAPTGAAKMT2AMEN1ALDH1A1
SCHEMBL2051864 0.77 GAA (0.33) GAA
SCHEMBL2051863 0.77 GAA (0.33) GAA
SCHEMBL2044914 0.76 GAA (0.33) GAA
SCHEMBL2046007 0.76 ALDH1A1 (0.30) ALDH1A1
SCHEMBL9897380 0.76 CYP1A2 (0.39)
SCHEMBL9897382 0.76 CYP1A2 (0.39)
SCHEMBL214990 0.73 GAA (0.41) MAPTGAAKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516475-B1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2020-10-07 EP claimed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US claimed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US claimed
EP-2516475-B1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2020-10-07 EP disclosed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US disclosed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed