Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.62 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.62 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.62 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.62 |
| ▸ | F2 | P00734 | 1/20 | 0.62 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.61 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | GBA1 | P04062 | 1/20 | 0.50 |
| ▸ | MDK | P21741 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL269540 | 0.97 | F2 (0.65) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL19679441 | 0.97 | F2 (0.65) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL30062300 | 0.97 | F2 (0.65) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL1164840 | 0.97 | F2 (0.65) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL30904598 | 0.96 | F2 (0.64) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL13041591 | 0.93 | F2 (0.60) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL15258705 | 0.93 | F2 (0.60) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL31135781 | 0.93 | TDP1 (0.61) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL31135784 | 0.93 | TDP1 (0.61) | PRSS1PRSS2PRSS3TPSAB1F2 | |
| SCHEMBL30735993 | 0.93 | TDP1 (0.61) | PRSS1PRSS2PRSS3TPSAB1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210369850-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | Centauri Therapeutics Limited (GB/GB) (GB) | 2021-12-02 | — | — | US | disclosed |
| US-10953100-B2 | Compounds and therapeutic uses thereof | CENTUARI THERAPEUTICS LIMITED (GB/GB) (GB) | 2021-03-23 | — | — | US | disclosed |
| US-20180280521-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | CENTUARI THERAPEUTICS LIMITED (GB/GB) (GB) | 2018-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369850-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | CD47, MYD88, NFATC1 | PRSS1 3209/4885PRSS2 3161/4885PRSS3 3932/4885 |
| US-10953100-B2 | Compounds and therapeutic uses thereof | CD47, MYD88, NFATC1 | PRSS1 3209/4885PRSS2 3161/4885PRSS3 3932/4885 |
| US-20180280521-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | CD47, MYD88, NFATC1 | PRSS1 3209/4885PRSS2 3161/4885PRSS3 3932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.