Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.65 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.65 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.65 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 3/20 | 0.61 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | IDE | P14735 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30062300 | 1.00 | F2 (0.65) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL19679441 | 1.00 | F2 (0.65) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL1164840 | 1.00 | F2 (0.65) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL30904598 | 0.99 | F2 (0.64) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL20519813 | 0.97 | PRSS1 (0.62) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL13041591 | 0.95 | F2 (0.60) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL15258705 | 0.95 | F2 (0.60) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL24313157 | 0.94 | F2 (0.60) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL10689008 | 0.94 | TDP1 (0.58) | F2PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL31135784 | 0.93 | TDP1 (0.61) | F2PRSS1PRSS2PRSS3TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10933142-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS LTD (GB) | 2021-03-02 | — | — | US | disclosed |
| US-20210040145-A1 | MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES | UNIV MUENCHEN LUDWIG MAXIMILIANS (DE) | 2021-02-11 | — | — | US | disclosed |
| US-10745437-B2 | Means and methods for site-specific functionalization of polypeptides | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2020-08-18 | — | — | US | disclosed |
| CN-104529711-B | Alkynes and methods of reacting alkynes with 1, 3-dipole-functional compounds | 乔治亚大学研究基金公司 | 2020-02-07 | — | — | CN | disclosed |
| US-10548982-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS LTD (GB) | 2020-02-04 | — | — | US | disclosed |
| US-20190142950-A1 | Reversible Covalent Linkage of Functional Molecules | UCL BUSINESS LTD (GB) | 2019-05-16 | — | — | US | disclosed |
| US-10208084-B2 | Means and methods for site-specific functionalization of polypeptides | LUDWIG-MAXIMILIANS-UNIVERSITÄT MÜNCHEN (DE) | 2019-02-19 | — | — | US | disclosed |
| US-10174094-B2 | Reversible covalent linkage of functional molecules | UCL BUSINESS PLC (GB) | 2019-01-08 | — | — | US | disclosed |
| EP-2907525-B1 | DIBENZOCYCLOOCTENE-COMPOUNDS FOR BIOORTHOGONAL REACTIONS | UNIV GEORGIA (US) | 2018-05-16 | — | — | EP | disclosed |
| US-9932297-B2 | Alkynes and methods of reacting alkynes with 1,3-dipole-functional compounds | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2018-04-03 | — | — | US | disclosed |
| US-8258347-B2 | Cyclopropenones and the photochemical generation of cyclic alkynes therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-09-04 | — | — | US | disclosed |
| US-20120190124-A1 | Reversible Covalent Linkage of Functional Molecules | UCL BUSINESS LTD (GB) | 2012-07-26 | — | — | US | disclosed |
| US-20120190579-A1 | Functionalisation of Solid Substrates | UCL BUSINESS PLC (GB) | 2012-07-26 | — | — | US | disclosed |
| US-20120172575-A1 | ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-07-05 | — | — | US | disclosed |
| US-8133515-B2 | Alkynes and methods of reacting alkynes with 1,3-dipole-functional compounds | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-20120053299-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-03-01 | — | — | US | disclosed |
| US-20120040011-A9 | ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| WO-2011018613-A1 | FUNCTIONALISATION OF SOLID SUBSTRATES | UCL BUSINESS PLC (GB) | 2011-02-17 | — | — | WO | disclosed |
| US-20100297250-A1 | ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2010-11-25 | — | — | US | disclosed |
| US-20100210854-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10174094-B2 | Reversible covalent linkage of functional molecules | F12, F13A1, F2 | F2 3/4885PRSS1 2739/4885PRSS2 3219/4885 |
| US-20120190124-A1 | Reversible Covalent Linkage of Functional Molecules | F12, F13A1, F2 | F2 3/4885PRSS1 2739/4885PRSS2 3219/4885 |
| US-20190142950-A1 | Reversible Covalent Linkage of Functional Molecules | F12, F13A1, F2 | F2 3/4885PRSS1 2739/4885PRSS2 3219/4885 |
| US-20120190579-A1 | Functionalisation of Solid Substrates | XDH, SPR, DAO | F2 564/4885PRSS1 191/4885PRSS2 405/4885 |
| US-20100297250-A1 | ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS | ALG1, ST3GAL3, B3GNT2 | F2 582/4885PRSS1 4207/4885PRSS2 4526/4885 |
| US-20120040011-A9 | ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS | ALG1, ST3GAL3, B3GNT2 | F2 582/4885PRSS1 4207/4885PRSS2 4526/4885 |
| US-20120053299-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | WEE1, WEE2, MPI | F2 3285/4885PRSS1 2629/4885PRSS2 3093/4885 |
| US-20210040145-A1 | MEANS AND METHODS FOR SITE-SPECIFIC FUNCTIONALIZATION OF POLYPEPTIDES | PTMS, DNPEP, LNPEP | F2 2920/4885PRSS1 1988/4885PRSS2 1430/4885 |
| US-10208084-B2 | Means and methods for site-specific functionalization of polypeptides | PTMS, DNPEP, LNPEP | F2 2920/4885PRSS1 1988/4885PRSS2 1430/4885 |
| US-10548982-B2 | Reversible covalent linkage of functional molecules | F12, F13A1, F2 | F2 3/4885PRSS1 2739/4885PRSS2 3219/4885 |
| US-20120172575-A1 | ALKYNES AND METHODS OF REACTING ALKYNES WITH 1,3-DIPOLE-FUNCTIONAL COMPOUNDS | ALG1, ST3GAL3, B3GNT2 | F2 582/4885PRSS1 4207/4885PRSS2 4526/4885 |
| US-10933142-B2 | Reversible covalent linkage of functional molecules | F12, F13A1, F2 | F2 3/4885PRSS1 2739/4885PRSS2 3219/4885 |
| US-10745437-B2 | Means and methods for site-specific functionalization of polypeptides | PTMS, DNPEP, LNPEP | F2 2920/4885PRSS1 1988/4885PRSS2 1430/4885 |
| US-20100210854-A1 | Cyclopropenones and the Photochemical Generation of Cyclic Alkynes Therefrom | WEE1, WEE2, MPI | F2 3285/4885PRSS1 2629/4885PRSS2 3093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.