SCHEMBL2052260

SCHEMBL2052260

c1ccc(N2CCCN2c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.44
KMT2A Q03164 3/20 0.44
SIGMAR1 Q99720 2/20 0.44
MEN1 O00255 2/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
HTR3E A5X5Y0 1/20 0.42
HTR3B O95264 1/20 0.42
ADRB1 P08588 1/20 0.42
HTR3A P46098 1/20 0.42
HTR3D Q70Z44 1/20 0.42
HTR3C Q8WXA8 1/20 0.42
RECQL P46063 1/20 0.42
LMNA P02545 1/20 0.42
MBTD1 Q05BQ5 1/20 0.40
L3MBTL3 Q96JM7 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
MAPK1 P28482 2/20 0.40
CYP3A4 P08684 2/20 0.39
CHRNA7 P36544 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28478724 0.92 KCNH2 (0.44) KMT2ASIGMAR1MEN1NPC1RAB9A
SCHEMBL2958249 0.87 SMN1; SMN2 (0.41) SMN1; SMN2KMT2ASIGMAR1MEN1NPC1
SCHEMBL10262716 0.83 GAA (0.41) SMN1; SMN2KMT2ASIGMAR1MEN1NPC1
SCHEMBL11974615 0.78 LMNA (0.56) SMN1; SMN2KMT2ASIGMAR1MEN1RAB9A
SCHEMBL12996175 0.78 CYP3A4 (0.40) SMN1; SMN2KMT2ASIGMAR1MEN1NPC1
SCHEMBL569307 0.77 LMNA (0.61) SMN1; SMN2KMT2ASIGMAR1MEN1NPC1
SCHEMBL16924863 0.77 LMNA (0.61) SMN1; SMN2KMT2ASIGMAR1MEN1NPC1
SCHEMBL21223444 0.75 SMN1; SMN2 (0.37) SMN1; SMN2KMT2AMEN1NPC1RAB9A
SCHEMBL577708 0.74 LMNA (0.58) SMN1; SMN2KMT2ASIGMAR1MEN1NPC1
SCHEMBL576673 0.74 LMNA (0.58) SMN1; SMN2KMT2ASIGMAR1MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4273873-A BONDING SYNTHETIC FIBRINOLYTIC COMPOUND OR ENZYME UNITIKA LTD. (JP) 1981-06-16 US claimed
US-20230042522-A1 INKJET COMPOSITION HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2023-02-09 US disclosed
US-20190241756-A1 SHIPPING FLUID HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2019-08-08 US disclosed
US-7964691-B2 5,5-diallyl-2,2-dimethyl-1,3-dioxane as monomer units; polymerization catalysts; heat resistance SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-21 US disclosed
WO-2009038031-A1 BLOCK COPOLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-26 WO disclosed
WO-2009038006-A1 RANDOM COPOLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-26 WO disclosed
US-20080214755-A1 OLEFIN-DIENE COPOLYMER AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-04 US disclosed
EP-0997503-B1 Light sensitive invisible ink compositions and methods for using the same HEWLETT PACKARD CO (US) 2005-06-01 EP disclosed
US-6513921-B1 Light sensitive invisible ink compositions and methods for using the same HEWLETT-PACKARD COMPANY 2003-02-04 US disclosed
US-6149719-A INKS WITH METAL PHTHALOCYANINE FLUOROPHORE FOR LIGHT ABSORPTION AND VEHICLES HEWLETT-PACKARD COMPANY (US) 2000-11-21 US disclosed
EP-0997503-A1 Light sensitive invisible ink compositions and methods for using the same Hewlett-Packard Company (US) 2000-05-03 EP disclosed
EP-0332922-A2 Pyrazolidinedione arylidene dye-donor element for thermal dye transfer EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1989-09-20 EP disclosed
EP-0185100-A1 PROCESS FOR PREPARING SILVER HALIDE EMULSION FUJI PHOTO FILM CO., LTD. (JP) 1986-06-25 EP disclosed
US-4273873-A BONDING SYNTHETIC FIBRINOLYTIC COMPOUND OR ENZYME UNITIKA LTD. (JP) 1981-06-16 US disclosed
US-3931406-A Pyrazolidine fungicides AMERICAN CYANAMID COMPANY (US) 1976-01-06 US disclosed