Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAF1 | P04049 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16461465 | 0.85 | KMT2A (0.38) | ALDH1A1HSD17B10CA1CA2CA12 | |
| SCHEMBL27432349 | 0.81 | CA1 (0.38) | ALDH1A1HSD17B10CA1CA2CA12 | |
| SCHEMBL1714508 | 0.79 | TSHR (0.35) | ALDH1A1CA1CA2CA12CA7 | |
| SCHEMBL2486113 | 0.79 | TSHR (0.35) | ALDH1A1CA1CA2CA12CA7 | |
| SCHEMBL1714160 | 0.79 | TSHR (0.35) | ALDH1A1CA1CA2CA12CA7 | |
| SCHEMBL9951422 | 0.77 | CA1 (0.42) | ALDH1A1HSD17B10CA1CA2CA12 | |
| SCHEMBL31401440 | 0.76 | TSHR (0.39) | ALDH1A1HSD17B10L3MBTL1GAATSHR | |
| SCHEMBL2364146 | 0.76 | USP2 (0.41) | USP2ALDH1A1HSD17B10CA1CA2 | |
| SCHEMBL31401142 | 0.75 | MAPT (0.35) | ALDH1A1L3MBTL1LMNAMAPT | |
| SCHEMBL29104732 | 0.72 | CA1 (0.41) | ALDH1A1HSD17B10CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3600327-A1 | HETEROCYCLIC COMPOUND | Cardurion Pharmaceuticals, LLC (US) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018183112-A1 | HETEROCYCLIC COMPOUND | CARDURION PHARMACEUTICALS, LLC (US) | 2018-10-04 | — | — | WO | disclosed |