SCHEMBL20522666

SCHEMBL20522666

COc1cc(NC(=O)C(N)CC(C)C)cc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 17/20 0.56
CIT O14578 1/20 0.52
LARS1 Q9P2J5 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5055276 1.00 AAK1 (0.56) AAK1CITLARS1
SCHEMBL7738208 0.86 TAAR1 (0.48) AAK1
SCHEMBL9115646 0.84 TNIK (0.43) AAK1
SCHEMBL11418814 0.84 AAK1 (0.42) AAK1CITLARS1
SCHEMBL4609875 0.81 LARS1 (0.43) AAK1CITLARS1
SCHEMBL1514737 0.79 KDM4E (0.41) AAK1
SCHEMBL28979891 0.79 KDM4E (0.41) AAK1
SCHEMBL1820784 0.78 LARS1 (0.64) AAK1CITLARS1
SCHEMBL21171627 0.78 LARS1 (0.64) AAK1CITLARS1
SCHEMBL30533426 0.78 LARS1 (0.64) AAK1CITLARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200405913-A1 INJECTABLE CELL AND SCAFFOLD COMPOSITIONS PROKIDNEY (KY) 2020-12-31 US disclosed
WO-2018183199-A1 INJECTABLE CELL AND SCAFFOLD COMPOSITIONS JAIN DEEPAK (US) 2018-10-04 WO disclosed