Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 9/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20522666 | 0.84 | AAK1 (0.56) | AAK1 | |
| SCHEMBL5055276 | 0.84 | AAK1 (0.56) | AAK1 | |
| SCHEMBL1514737 | 0.83 | KDM4E (0.41) | TNIKROCK2ROCK1GAAKMT2A | |
| SCHEMBL28979891 | 0.83 | KDM4E (0.41) | TNIKROCK2ROCK1GAAKMT2A | |
| SCHEMBL6820161 | 0.82 | LTA4H (0.55) | TNIKKMT2AKDM4EALDH1A1NPSR1 | |
| SCHEMBL6820163 | 0.82 | LTA4H (0.55) | TNIKKMT2AKDM4EALDH1A1NPSR1 | |
| SCHEMBL7715008 | 0.82 | LTA4H (0.55) | KMT2AKDM4EALDH1A1NPSR1RXFP1 | |
| SCHEMBL7738208 | 0.82 | TAAR1 (0.48) | TNIKKMT2AAAK1KDM4EALDH1A1 | |
| SCHEMBL20460454 | 0.81 | AAK1 (0.43) | ROCK2ROCK1GAAKMT2AAAK1 | |
| SCHEMBL21753952 | 0.78 | MEN1 (0.50) | ROCK2ROCK1GAAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995012679-A1 | ANTI-HELMINTH VACCINES | BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL (GB) | 1995-05-11 | — | — | WO | disclosed |