Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20523104 | 0.99 | MAP3K5 (0.59) | MAP3K5 | |
| SCHEMBL20523071 | 0.94 | MAP3K5 (0.59) | MAP3K5 | |
| SCHEMBL20522708 | 0.90 | MAP3K5 (0.57) | MAP3K5 | |
| Hydrochloric Acid SCHEMBL20523105 | 0.90 | MAP3K5 (0.56) | MAP3K5 | |
| SCHEMBL20523072 | 0.86 | MAP3K5 (0.56) | MAP3K5 | |
| Hydrochloric Acid SCHEMBL21681086 | 0.85 | MAP3K5 (0.56) | MAP3K5 | |
| SCHEMBL20523033 | 0.83 | MAP3K5 (0.76) | MAP3K5 | |
| SCHEMBL20522944 | 0.82 | MAP3K5 (0.71) | MAP3K5 | |
| SCHEMBL20523363 | 0.80 | MAP3K5 (0.91) | MAP3K5 | |
| SCHEMBL934010 | 0.80 | MAP3K5 (0.64) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601250-A1 | APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK 1) INHIBITOR COMPOUNDS | Pharmakea, Inc. (US) | 2020-02-05 | — | — | EP | claimed |
| WO-2018183122-A1 | APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK 1) INHIBITOR COMPOUNDS | SIDECAR THERAPEUTICS, INC. (US) | 2018-10-04 | — | — | WO | claimed |
| EP-3601250-A1 | APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK 1) INHIBITOR COMPOUNDS | Pharmakea, Inc. (US) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018183122-A1 | APOPTOSIS SIGNAL-REGULATING KINASE 1 (ASK 1) INHIBITOR COMPOUNDS | SIDECAR THERAPEUTICS, INC. (US) | 2018-10-04 | — | — | WO | disclosed |