Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 19/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008287 | 0.92 | LTA4H (0.60) | LTA4HKCNH2 | |
| SCHEMBL1006924 | 0.83 | LTA4H (0.59) | LTA4HKCNH2 | |
| SCHEMBL12356790 | 0.82 | LTA4H (0.55) | LTA4HKCNH2 | |
| SCHEMBL2169505 | 0.78 | LTA4H (0.74) | LTA4HKCNH2 | |
| SCHEMBL2169442 | 0.77 | LTA4H (0.75) | LTA4HKCNH2 | |
| SCHEMBL1007942 | 0.76 | LTA4H (0.56) | LTA4HKCNH2 | |
| SCHEMBL1010682 | 0.76 | LTA4H (0.57) | LTA4HKCNH2 | |
| Hydrochloric Acid SCHEMBL1895789 | 0.76 | LTA4H (0.56) | LTA4HKCNH2 | |
| SCHEMBL1882089 | 0.75 | LTA4H (0.84) | LTA4HKCNH2 | |
| SCHEMBL4964452 | 0.75 | LTA4H (0.75) | LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2336125-A1 | Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase | Janssen Pharmaceutica N.V. (BE) | 2011-06-22 | — | — | EP | disclosed |