Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42956 | 0.93 | ALDH1A1 (0.48) | CA1CA12CA2CA9ALDH1A1 | |
| SCHEMBL17401248 | 0.90 | ALDH1A1 (0.46) | CA1CA12CA2CA9ALDH1A1 | |
| SCHEMBL9945700 | 0.90 | ALDH1A1 (0.46) | CA1CA12CA2CA9ALDH1A1 | |
| SCHEMBL9945703 | 0.90 | ALDH1A1 (0.46) | CA1CA12CA2CA9ALDH1A1 | |
| Magnesium SCHEMBL8463764 | 0.90 | ALDH1A1 (0.46) | CA1CA12CA2CA9ALDH1A1 | |
| SCHEMBL10389154 | 0.90 | ALDH1A1 (0.46) | CA1CA12CA2CA9ALDH1A1 | |
| Potassium SCHEMBL2529395 | 0.90 | ALDH1A1 (0.46) | CA1CA12CA2CA9ALDH1A1 | |
| SCHEMBL4323031 | 0.90 | ALDH1A1 (0.46) | CA1CA12CA2CA9ALDH1A1 | |
| Ethane SCHEMBL887641 | 0.90 | ALDH1A1 (0.46) | CA1CA12CA2CA9ALDH1A1 | |
| SCHEMBL9452585 | 0.90 | ALDH1A1 (0.46) | CA1CA12CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601286-A1 | NOVEL CRYSTAL FORMS OF A POL1 INHIBITOR | Pimera, Inc. (US) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018183540-A1 | NOVEL CRYSTAL FORMS OF A POL1 INHIBITOR | Pimera, Inc. (US) | 2018-10-04 | — | — | WO | disclosed |
| CN-103421172-B | A kind of purifying process of biodegradable polyesters | SHANGHAI MODERN NATIONAL PHARMACEUTICAL ENGINEERING RESEARCH CENTER CO., LTD. (CN) | 2016-01-20 | — | — | CN | disclosed |
| CN-103421172-A | Purification technique of biodegradable polyesters | SHANGHAI MODERN PHARMACEUTICAL ENGINEERING RES CT CO LTD | 2013-12-04 | — | — | CN | disclosed |