Methane

Methane

SCHEMBL205249

C.CC(=O)O[SiH2]OC(C)=O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
TSHR P16473 3/20 0.41
LMNA P02545 3/20 0.33
HSD17B10 Q99714 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
THPO P40225 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203137 0.96
SCHEMBL27805582 0.93 ALDH1A1 (0.41) ALDH1A1TSHRLMNAHSD17B10TDP1
Methane SCHEMBL29067002 0.84
Butane SCHEMBL6454649 0.84 ALDH1A1 (0.41) ALDH1A1TSHRLMNAHSD17B10TDP1
SCHEMBL11579035 0.83 ALDH1A1 (0.39) ALDH1A1TSHRLMNAHSD17B10TDP1
Propene SCHEMBL27618700 0.82 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10TDP1
Butadiene SCHEMBL17498997 0.82 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL5391067 0.80 TDP1 (0.44) ALDH1A1TSHRHSD17B10TDP1
SCHEMBL21295313 0.80 ALDH1A1 (0.43) ALDH1A1TSHRLMNAHSD17B10TDP1
SCHEMBL2293086 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1620479-A1 POLYOLEFIN ADHESIVE COMPOSITIONS AND ARTICLES MADE THEREFROM Exxonmobil Chemical Patents Inc. (US) 2006-02-01 EP claimed
WO-2005108442-A1 POLYOLEFIN ADHESIVE COMPOSITIONS AND ARTICLES MADE THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-17 WO claimed
US-20040127614-A1 a Dot T-Peel of 1 Newton or more on Kraft paper; molecualr weight of 10,000 to 100,000; and a branching index (g') of 0.98 or less EXXONMOBIL CHEMICAL PATENTS INC. 2004-07-01 US claimed
US-11814553-B2 Adhesive DOW SILICONES CORPORATION (US) 2023-11-14 US disclosed
US-20210380856-A1 ADHESIVE DOW SILICONES CORPORATION 2021-12-09 US disclosed
EP-3874003-A1 ADHESIVE Dow Silicones Corporation (US) 2021-09-08 EP disclosed
EP-1866374-B1 ORGANOSILOXANE COMPOSITIONS DOW CORNING (US) 2016-06-08 EP disclosed
EP-1866376-B1 ORGANOSILOXANE COMPOSITIONS DOW CORNING (US) 2015-05-20 EP disclosed
EP-1874868-B1 ORGANOSILOXANE COMPOSITIONS DOW CORNING (US) 2015-05-20 EP disclosed
EP-1866375-B1 ORGANOSILOXANE COMPOSITIONS DOW CORNING (US) 2015-01-28 EP disclosed
US-8524828-B2 Polymeric compositions DOW CORNING CORPORATION (US) 2013-09-03 US disclosed
US-20040127614-A1 a Dot T-Peel of 1 Newton or more on Kraft paper; molecualr weight of 10,000 to 100,000; and a branching index (g') of 0.98 or less EXXONMOBIL CHEMICAL PATENTS INC. 2004-07-01 US disclosed
EP-1040165-B1 A POLYSILOXANE HAVING A COPOLYMER DISPERSED THEREIN AND SEALANTS CONTAINING THE SAME TREMCO INC (US) 2002-06-12 EP disclosed
US-6403711-B1 BINDER IN CAULKS AND SEALANTS; ADDITION FREE RADICALLY POLYMERIZING LOW AND HIGH TG POLYMER-FORMING MONOMERS IN THE PRESENCE OF POLYSILOXANE NOVEON IP HOLDINGS CORP. 2002-06-11 US disclosed
EP-1040165-A1 A POLYSILOXANE HAVING A COPOLYMER DISPERSED THEREIN AND SEALANTS CONTAINING THE SAME The B.F. Goodrich Company (US) 2000-10-04 EP disclosed
WO-1999031179-A1 A POLYSILOXANE HAVING A COPOLYMER DISPERSED THEREIN AND SEALANTS CONTAINING THE SAME THE B.F. GOODRICH COMPANY (US) 1999-06-24 WO disclosed
EP-0302712-B1 Novel copolycarbonate ASAHI CHEMICAL IND (JP) 1996-11-13 EP disclosed
US-5070173-A POLYCARBONATEURETHANE THERMOPLASTIC ELASTOMERS; RESISTANT TO H YDROLYSIS, LIGHT, CHLORINE AND OXIDATION ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1991-12-03 US disclosed
US-4855377-A Novel copolycarbonate ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1989-08-08 US disclosed
EP-0302712-A2 Novel copolycarbonate Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1989-02-08 EP disclosed