Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18095786 | 0.87 | POLB (0.60) | ANPEPPOLBMAOASLC6A2TAAR1 | |
| SCHEMBL1132867 | 0.85 | CA1 (0.53) | — | |
| SCHEMBL1132538 | 0.85 | CA1 (0.53) | — | |
| SCHEMBL17509718 | 0.81 | ANPEP (0.62) | ANPEPSLC6A2SLC6A4SLC6A3APAF1 | |
| SCHEMBL20525326 | 0.77 | ANPEP (0.49) | ANPEPSLC6A2SLC6A4SLC6A3APAF1 | |
| SCHEMBL20525547 | 0.75 | ANPEP (0.47) | ANPEPMAOASLC6A2TAAR1SLC6A4 | |
| SCHEMBL18575556 | 0.74 | SLC6A2 (0.42) | POLBSLC6A2TAAR1SLC6A4SLC6A3 | |
| SCHEMBL17509721 | 0.72 | MTOR (0.56) | ANPEPPOLBMAOASLC6A2TAAR1 | |
| SCHEMBL9188260 | 0.69 | SIGMAR1 (0.63) | MAOASLC6A2TAAR1SLC6A4SLC6A3 | |
| SCHEMBL1133278 | 0.69 | CA1 (0.48) | POLBADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3180382-B1 | AMINE FOR LOW-EMISSION EPOXY RESIN COMPOSITIONS | SIKA TECH AG (CH) | 2018-10-10 | — | — | EP | disclosed |