SCHEMBL20525918

SCHEMBL20525918

CCc1ccc(Cn2c(CCc3ccccc3)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)CN)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3636106 1.00 GHSR (1.00) GHSR
SCHEMBL5604252 0.92 GHSR (1.00) GHSR
SCHEMBL3679310 0.92 GHSR (1.00) GHSR
SCHEMBL2742698 0.92 GHSR (1.00) GHSR
SCHEMBL20525931 0.90 GHSR (0.81) GHSR
SCHEMBL3674671 0.90 GHSR (0.81) GHSR
SCHEMBL3637135 0.89 GHSR (1.00) GHSR
SCHEMBL3637137 0.89 GHSR (1.00) GHSR
SCHEMBL20525920 0.88 GHSR (0.78) GHSR
SCHEMBL3632427 0.88 GHSR (0.78) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1915149-B1 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS AETERNA ZENTARIS GMBH (DE) 2018-10-10 — — EP claimed
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