SCHEMBL20525942

SCHEMBL20525942

O=C(NC(Cc1c[nH]c2ccccc12)c1nnc(Cc2ccccc2)n1Cc1ccccn1)c1ccccn1

nearest known ligand 0.69

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 20/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3637491 1.00 GHSR (0.69) GHSR
SCHEMBL20525915 0.93 GHSR (0.72) GHSR
SCHEMBL3638501 0.93 GHSR (0.72) GHSR
SCHEMBL20525948 0.89 GHSR (0.66) GHSR
SCHEMBL3679051 0.89 GHSR (0.66) GHSR
SCHEMBL4106575 0.89 GHSR (0.69) GHSR
SCHEMBL3636875 0.87 GHSR (0.84) GHSR
SCHEMBL3636877 0.87 GHSR (0.84) GHSR
SCHEMBL4113313 0.86 GHSR (0.77) GHSR
SCHEMBL20525899 0.85 GHSR (0.74) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1915149-B1 NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS AETERNA ZENTARIS GMBH (DE) 2018-10-10 — — EP claimed
CN-101272782-B Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors AETERNA ZENTARIS GMBH 2012-03-14 — — CN claimed
CN-101272782-A Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors AETERNA ZENTARIS GMBH (DE) 2008-09-24 — — CN claimed
CN-101272782-B Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors AETERNA ZENTARIS GMBH 2012-03-14 — — CN disclosed
CN-101687011-A Novel treatment for chemical substance addiction DICKSON SUZANNE L 2010-03-31 — — CN disclosed
CN-101272782-A Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors AETERNA ZENTARIS GMBH (DE) 2008-09-24 — — CN disclosed
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