SCHEMBL20526641

SCHEMBL20526641

O=Cc1ccc(-n2c3ccccc3c3cc(F)ccc32)cc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 1/20 0.48
JAK3 P52333 1/20 0.48
ALDH1A1 P00352 6/20 0.46
KDM4E B2RXH2 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.44
ATM Q13315 2/20 0.44
PTGER4 P35408 2/20 0.43
CYP1A2 P05177 1/20 0.38
METAP2 P50579 1/20 0.38
HTT P42858 2/20 0.37
LMNA P02545 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
TDP1 Q9NUW8 1/20 0.36
HKDC1 Q2TB90 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28370714 0.88 KDM4E (0.50) ALDH1A1KDM4EL3MBTL1ATMPTGER4
SCHEMBL17513001 0.88 KDM4E (0.54) ALDH1A1KDM4EL3MBTL1ATMPTGER4
SCHEMBL30462688 0.86 KDM4E (0.59) ALDH1A1KDM4EL3MBTL1ATMPTGER4
SCHEMBL29387787 0.86 KDM4E (0.59) ALDH1A1KDM4EL3MBTL1ATMPTGER4
SCHEMBL39208 0.86 KDM4E (0.59) ALDH1A1KDM4EL3MBTL1ATMPTGER4
SCHEMBL23126869 0.84 KDM4E (0.47) ALDH1A1KDM4EL3MBTL1ATMPTGER4
SCHEMBL20239634 0.82 ATM (0.67) JAK2JAK3ALDH1A1KDM4EL3MBTL1
SCHEMBL18892915 0.82 KDM4E (0.49) ALDH1A1KDM4EL3MBTL1ATMPTGER4
SCHEMBL17512995 0.82 ALDH1A1 (0.46) ALDH1A1KDM4EL3MBTL1ATMPTGER4
SCHEMBL3659204 0.82 PTGER4 (0.51) ALDH1A1KDM4EL3MBTL1ATMPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12268088-B2 Light emission material and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2025-04-01 US disclosed
US-20240431204-A1 LIGHT EMISSION MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-12-26 US disclosed
US-20180294419-A1 LIGHT EMISSION MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-10-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12268088-B2 Light emission material and organic electroluminescence device including the same CCNT1, L1CAM, CCNE2 JAK2 2323/4885JAK3 786/4885ALDH1A1 623/4885
US-20180294419-A1 LIGHT EMISSION MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CCNT1, L1CAM, CCNE2 JAK2 2323/4885JAK3 786/4885ALDH1A1 623/4885
US-20240431204-A1 LIGHT EMISSION MATERIAL AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME CCNE2, CCNT1, NES JAK2 2098/4885JAK3 540/4885ALDH1A1 1037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.