SCHEMBL20527637

SCHEMBL20527637

C[n+]1ccn(CC(=O)c2ccc(Cl)cc2)c1

nearest known ligand 0.97

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.72
SMN1; SMN2 Q16637 1/20 0.72
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
RECQL P46063 1/20 0.47
RAB9A P51151 1/20 0.43
GSK3B P49841 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
PABPC1 P11940 1/20 0.42
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CXCR3 P49682 2/20 0.41
IDO1 P14902 1/20 0.41
PKM P14618 1/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10531134 0.86 SMN1; SMN2 (0.74) LMNASMN1; SMN2MEN1KMT2ARECQL
Bromide SCHEMBL10850394 0.85 SMN1; SMN2 (0.76) LMNASMN1; SMN2MEN1KMT2ARECQL
SCHEMBL20527600 0.85 SMN1; SMN2 (0.97) LMNASMN1; SMN2MEN1KMT2ARECQL
SCHEMBL20527454 0.84 LMNA (0.63) LMNASMN1; SMN2CA12CA1CA2
SCHEMBL20527661 0.84 LMNA (0.59) LMNASMN1; SMN2MEN1KMT2ARECQL
Bromide SCHEMBL3850911 0.84 SMN1; SMN2 (0.74) LMNASMN1; SMN2CA12CA1CA2
Bromide SCHEMBL3845988 0.84 SMN1; SMN2 (1.00) LMNASMN1; SMN2MEN1KMT2ARECQL
Bromide SCHEMBL3844582 0.83 LMNA (0.74) LMNASMN1; SMN2MEN1KMT2ARECQL
SCHEMBL20527467 0.82 LMNA (0.68) LMNASMN1; SMN2MEN1KMT2ARECQL
Hydrochloric Acid SCHEMBL3847700 0.81 SMN1; SMN2 (0.52) LMNASMN1; SMN2CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11377535-B2 Carbon fiber recovery compositions and methods THE BOEING COMPANY (US) 2022-07-05 US claimed
US-20200207940-A1 Carbon Fiber Recovery Compositions and Methods THE BOEING COMPANY 2020-07-02 US claimed
US-10611892-B2 Carbon fiber recovery compositions and methods THE BOEING COMPANY (US) 2020-04-07 US claimed
US-20180291174-A1 Carbon Fiber Recovery Compositions and Methods THE BOEING COMPANY 2018-10-11 US claimed
US-11377535-B2 Carbon fiber recovery compositions and methods THE BOEING COMPANY (US) 2022-07-05 US disclosed
US-20200207940-A1 Carbon Fiber Recovery Compositions and Methods THE BOEING COMPANY 2020-07-02 US disclosed
US-10611892-B2 Carbon fiber recovery compositions and methods THE BOEING COMPANY (US) 2020-04-07 US disclosed
US-20180291174-A1 Carbon Fiber Recovery Compositions and Methods THE BOEING COMPANY 2018-10-11 US disclosed