Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14517181 | 0.60 | — | — | |
| SCHEMBL5872467 | 0.59 | — | — | |
| SCHEMBL943630 | 0.54 | — | — | |
| SCHEMBL19439652 | 0.52 | — | — | |
| SCHEMBL22350887 | 0.51 | — | — | |
| SCHEMBL14767874 | 0.48 | — | — | |
| SCHEMBL14700667 | 0.48 | — | — | |
| SCHEMBL10411447 | 0.46 | — | — | |
| SCHEMBL5872408 | 0.45 | — | — | |
| SCHEMBL17022560 | 0.44 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859451-B2 | Process for the preparation of supported catalysts | BASELL POLYOLEFINE GMBH (DE) | 2014-10-14 | — | — | US | disclosed |
| US-20120283400-A1 | Process for the Preparation of Supported Catalysts | BASELL POLYOLEFINE GMBH (DE) | 2012-11-08 | — | — | US | disclosed |
| EP-2513166-A1 | PROCESS FOR THE PREPARATION OF SUPPORTED CATALYSTS | Basell Polyolefine GmbH (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-2367854-A1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE | Basell Polyolefine GmbH (DE) | 2011-09-28 | — | — | EP | disclosed |
| WO-2011072851-A1 | PROCESS FOR THE PREPARATION OF SUPPORTED CATALYSTS | BASELL POLYOLEFINE GMBH (DE) | 2011-06-23 | — | — | WO | disclosed |
| WO-2010069527-A1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE | BASELL POLYOLEFINE GMBH (DE) | 2010-06-24 | — | — | WO | disclosed |
| EP-1740626-A1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE | Basell Polyolefine GmbH (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005103099-A1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE | BASELL POLYOLEFINE GMBH (DE) | 2005-11-03 | — | — | WO | disclosed |