SCHEMBL20528003

SCHEMBL20528003

C=CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(=O)O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.63
PPARG P37231 8/20 0.63
CYP19A1 P11511 6/20 0.63
FFAR1 O14842 5/20 0.63
MAPT P10636 5/20 0.63
OXER1 Q8TDS5 4/20 0.63
RXRA P19793 2/20 0.63
F7 P08709 7/20 0.48
F3 P13726 7/20 0.48
PPARD Q03181 6/20 0.48
PPARA Q07869 6/20 0.48
PTGS1 P23219 4/20 0.48
KMT2A Q03164 3/20 0.48
ADORA3 P0DMS8 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.47
KDM4E B2RXH2 3/20 0.47
LMNA P02545 3/20 0.47
CYP3A4 P08684 3/20 0.47
HPGD P15428 3/20 0.47
ALOX15 P16050 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14317851 1.00 ALDH1A1 (0.63) ALDH1A1PPARGCYP19A1FFAR1MAPT
SCHEMBL27948496 1.00 ALDH1A1 (0.63) ALDH1A1PPARGCYP19A1FFAR1MAPT
SCHEMBL2575707 0.98 ALDH1A1 (0.59) ALDH1A1PPARGCYP19A1FFAR1MAPT
SCHEMBL8017585 0.98 ALDH1A1 (0.59) ALDH1A1PPARGCYP19A1FFAR1MAPT
SCHEMBL2575705 0.98 ALDH1A1 (0.59) ALDH1A1PPARGCYP19A1FFAR1MAPT
SCHEMBL29574065 0.89 ALDH1A1 (0.61) ALDH1A1PPARGCYP19A1FFAR1MAPT
SCHEMBL28742696 0.87 ALDH1A1 (0.66) ALDH1A1PPARGCYP19A1FFAR1MAPT
SCHEMBL466115 0.85 F7 (0.67) ALDH1A1PPARGCYP19A1FFAR1MAPT
SCHEMBL12000570 0.85 F7 (0.67) ALDH1A1PPARGCYP19A1FFAR1MAPT
SCHEMBL466116 0.85 F7 (0.67) ALDH1A1PPARGCYP19A1FFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113195447-A Composition containing eicosapentaenoic acid alkyl ester and method for producing same 日清药业股份有限公司 2021-07-30 CN claimed
US-12275699-B2 Eicosapentaenoic acid alkyl ester-containing composition and method for producing same NISSHIN PHARMA INC. (JP) 2025-04-15 US disclosed
US-11479802-B2 Assays for screening activity of modulators of members of the hydroxy steroid (17-beta) dehydrogenase (HSD17B) family REGENERON PHARMACEUTICALS, INC. (US) 2022-10-25 US disclosed
CN-113195447-A Composition containing eicosapentaenoic acid alkyl ester and method for producing same 日清药业股份有限公司 2021-07-30 CN disclosed
EP-3610029-A1 ASSAYS FOR SCREENING ACTIVITY OF MODULATORS OF MEMBERS OF THE HYDROXYSTEROID (17-BETA) DEHYDROGENASE (HSD17B) FAMILY Regeneron Pharmaceuticals, Inc. (US) 2020-02-19 EP disclosed
WO-2018190970-A1 ASSAYS FOR SCREENING ACTIVITY OF MODULATORS OF MEMBERS OF THE HYDROXYSTEROID (17-BETA) DEHYDROGENASE (HSD17B) FAMILY REGENERON PHARMACEUTICALS, INC. (US) 2018-10-18 WO disclosed
US-20180291422-A1 Assays For Screening Activity Of Modulators Of Members Of The Hydroxysteroid (17-Beta) Dehydrogenase (HSD17B) Family REGENERON PHARMACEUTICALS, INC. 2018-10-11 US disclosed