Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13387483 | 0.85 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9ALMNACTSK | |
| SCHEMBL13506655 | 0.85 | NPSR1 (0.58) | SMN1; SMN2NPC1RAB9ALMNACTSK | |
| SCHEMBL9359270 | 0.84 | ATM (0.50) | SMN1; SMN2NPC1RAB9ALMNAPOLB | |
| SCHEMBL7357011 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1RAB9ALMNACTSK | |
| SCHEMBL9317172 | 0.84 | POLB (0.58) | SMN1; SMN2NPC1RAB9ALMNACTSK | |
| SCHEMBL9848391 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ALMNACTSK | |
| SCHEMBL9848476 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ALMNACTSK | |
| SCHEMBL7454120 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ALMNACTSK | |
| SCHEMBL1461981 | 0.82 | ATM (0.60) | SMN1; SMN2NPC1RAB9ALMNACTSK | |
| SCHEMBL11491274 | 0.82 | ATM (0.60) | SMN1; SMN2NPC1RAB9ALMNACTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076784-A2 | NEW INHIBITORS OF CYCLOPHILINS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-06-30 | — | — | WO | disclosed |