Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 3/20 | 0.53 |
| ▸ | GPR88 | Q9GZN0 | 5/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848391 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ALMNAFAAH | |
| SCHEMBL844472 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9ALMNAFAAH | |
| SCHEMBL14040614 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9ALMNAFAAH | |
| SCHEMBL7454120 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ALMNAFAAH | |
| SCHEMBL7789635 | 0.85 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9ALMNAFAAH | |
| SCHEMBL8121337 | 0.85 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9ALMNAFAAH | |
| SCHEMBL349655 | 0.84 | FAAH (0.52) | SMN1; SMN2NPC1RAB9ALMNAFAAH | |
| SCHEMBL3630691 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ALMNAFAAH | |
| SCHEMBL4385673 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ALMNAFAAH | |
| SCHEMBL27648565 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9ALMNAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108349879-A | Synthesis of cyclohexanecarboxamide derivatives useful as sensates in consumer products | 宝洁公司 | 2018-07-31 | — | — | CN | disclosed |
| EP-0432442-A1 | ACAT inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |