Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15533388 | 0.86 | DPP4 (0.47) | DPP4OPRM1OPRK1 | |
| SCHEMBL5335575 | 0.76 | DPP4 (0.45) | DPP4OPRM1OPRK1 | |
| SCHEMBL15533861 | 0.74 | DPP4 (0.43) | DPP4 | |
| SCHEMBL15533200 | 0.72 | DPP4 (0.42) | DPP4 | |
| SCHEMBL28018613 | 0.72 | DPP4 (0.36) | DPP4OPRM1OPRK1 | |
| SCHEMBL6674842 | 0.68 | DPP4 (0.39) | DPP4 | |
| SCHEMBL16476640 | 0.68 | DPP4 (0.51) | DPP4OPRM1OPRK1 | |
| SCHEMBL27600222 | 0.68 | TSHR (0.39) | DPP4 | |
| SCHEMBL639135 | 0.68 | DPP4 (1.00) | DPP4 | |
| SCHEMBL15516850 | 0.68 | DPP4 (0.53) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180291025-A1 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BOEHRINGER INGELHEIM INT (DE) | 2018-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180291025-A1 | 8-[3-AMINO-PIPERIDIN-1-YL]-XANTHINES, THE PREPARATION THEREOF AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | DPP8, DPP4, DPP3 | DPP4 2/4885OPRM1 428/4885OPRK1 501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.