Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 8/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335575 | 0.68 | DPP4 (0.45) | TSHRALDH1A1DPP4HSD17B10HPGD | |
| SCHEMBL20528287 | 0.68 | DPP4 (0.51) | DPP4 | |
| SCHEMBL15533388 | 0.68 | DPP4 (0.47) | DPP4 | |
| SCHEMBL160189 | 0.67 | DPP4 (0.53) | DPP4KCNH2 | |
| SCHEMBL15516850 | 0.67 | DPP4 (0.53) | DPP4KCNH2 | |
| SCHEMBL7533607 | 0.66 | DPP4 (0.36) | DPP4KCNH2 | |
| SCHEMBL15533861 | 0.64 | DPP4 (0.43) | DPP4KCNH2 | |
| SCHEMBL9392201 | 0.62 | DAO (0.49) | TSHRALDH1A1POLBTDP1LMNA | |
| SCHEMBL27583093 | 0.62 | DPP4 (0.59) | TSHRALDH1A1ALOX15DPP4LMNA | |
| SCHEMBL25285380 | 0.62 | SLC6A3 (0.61) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1492870-A | Xanthine derivatives, process for their preparation and their use as pharmaceutical compositions | ���ָ��Ӣ��ķ�������Ϲ�˾ | 2004-04-28 | — | — | CN | disclosed |