Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27850992 | 0.79 | HRH3 (0.42) | HRH3HTR1DHTR1BCYP11B1CYP11B2 | |
| SCHEMBL12802677 | 0.79 | HRH3 (0.42) | HRH3HTR1DHTR1BCYP11B1CYP11B2 | |
| SCHEMBL1610963 | 0.79 | HRH3 (0.42) | HRH3HTR1DHTR1BCYP11B1CYP11B2 | |
| SCHEMBL27995904 | 0.79 | HRH3 (0.54) | HRH3HTR1DHTR1BCYP11B1CYP11B2 | |
| SCHEMBL8507988 | 0.78 | ALDH1A1 (0.33) | CYP11B1CYP11B2RAPGEF4MEN1KMT2A | |
| SCHEMBL900740 | 0.75 | HRH3 (0.38) | HRH3HTR1DHTR1BCYP11B1CYP11B2 | |
| SCHEMBL12802111 | 0.73 | HRH3 (0.41) | HRH3HTR1DHTR1BCYP11B1CYP11B2 | |
| SCHEMBL1609708 | 0.73 | HRH3 (0.41) | HRH3HTR1DHTR1BCYP11B1CYP11B2 | |
| SCHEMBL10912798 | 0.73 | HRH3 (0.41) | HRH3HTR1DHTR1BCYP11B1CYP11B2 | |
| SCHEMBL28813912 | 0.73 | HRH3 (0.41) | HRH3HTR1DHTR1BCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607002-A1 | COLORANT MIXTURES | Huntsman Advanced Materials (Switzerland) GmbH (CH) | 2020-02-12 | — | — | EP | disclosed |
| WO-2018184770-A1 | COLORANT MIXTURES | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) | 2018-10-11 | — | — | WO | disclosed |