SCHEMBL20528655

SCHEMBL20528655

C[CH]CCc1ccc(C)cc1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
TP53 P04637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NR3C1 P04150 1/20 0.36
PGR P06401 1/20 0.36
NR3C2 P08235 1/20 0.36
KMT2A Q03164 2/20 0.36
RAB9A P51151 2/20 0.35
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TNF P01375 1/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8508767 0.83 TAAR1 (0.59) TAAR1KDM4EALDH1A1TP53TDP1
SCHEMBL6547406 0.82 TAAR1 (0.48) PYCR1TAAR1KDM4EALDH1A1TP53
SCHEMBL1610182 0.82 PYCR1 (0.42) PYCR1TAAR1KDM4EALDH1A1TP53
SCHEMBL12802092 0.82 PYCR1 (0.39) PYCR1TAAR1SLC6A4KDM4EALDH1A1
SCHEMBL16644625 0.82 PYCR1 (0.39) PYCR1TAAR1KDM4EALDH1A1TP53
SCHEMBL585890 0.82 KDM4E (0.40) PYCR1TAAR1KDM4EALDH1A1TP53
SCHEMBL27463472 0.80 NR3C2 (0.39) SLC6A4NR3C2
SCHEMBL8508177 0.80 TAAR1 (0.37) TAAR1
SCHEMBL8508748 0.76 TAAR1 (0.41) TAAR1SLC6A4RAB9A
SCHEMBL5571847 0.76 TAAR1 (0.38) PYCR1TAAR1KDM4EALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3607002-A1 COLORANT MIXTURES Huntsman Advanced Materials (Switzerland) GmbH (CH) 2020-02-12 EP disclosed
WO-2018184770-A1 COLORANT MIXTURES HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2018-10-11 WO disclosed
CN-1239957-A Substituting 2-amino-4-alkylamino-1,3,5-triazine as herbicide BAYER AG (DE) 1999-12-29 CN disclosed