Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 15/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26968022 | 0.89 | HDAC6 (0.53) | HDAC6HDAC1HDAC5HDAC8HDAC4 | |
| Hydrochloric Acid SCHEMBL20528676 | 0.85 | HDAC6 (0.63) | HDAC6HDAC1HDAC5HDAC8HDAC4 | |
| SCHEMBL18920711 | 0.85 | HDAC6 (0.51) | HDAC6HDAC1HDAC5HDAC8HDAC4 | |
| SCHEMBL22531084 | 0.83 | HDAC6 (0.61) | HDAC6HDAC1HDAC5HDAC8HDAC4 | |
| SCHEMBL20528693 | 0.81 | HDAC6 (0.49) | HDAC6HDAC1HDAC5HDAC8HDAC4 | |
| SCHEMBL18398630 | 0.81 | HDAC4 (0.51) | HDAC6HDAC1HDAC5HDAC4 | |
| SCHEMBL23667729 | 0.80 | L3MBTL1 (0.53) | HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL20528700 | 0.79 | HDAC1 (0.47) | HDAC6HDAC1HDAC5HDAC8 | |
| SCHEMBL20528666 | 0.79 | HDAC6 (0.56) | HDAC6HDAC1HDAC5HDAC8HDAC4 | |
| SCHEMBL19745335 | 0.79 | HDAC6 (1.00) | HDAC6HDAC1HDAC5HDAC8HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018219773-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-12-06 | — | — | WO | disclosed |
| WO-2018184987-A1 | MICROBIOCIDAL OXADIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-10-11 | — | — | WO | disclosed |