Moxalactam

Moxalactam

SCHEMBL20528908

CO[C@@]1(NC(=O)C(C(=O)[O-])c2ccc(O)cc2)C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CO[C@@H]21.[Na+].[Na+].[NaH]

nearest known ligand 0.99

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Moxalactam. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.99
TDP1 Q9NUW8 1/20 0.99
PTGS1 P23219 1/20 0.79
CMA1 P23946 18/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Moxalactam SCHEMBL719333 0.99 HSD17B10 (1.00) HSD17B10TDP1PTGS1CMA1
Moxalactam SCHEMBL30166493 0.99 HSD17B10 (1.00) HSD17B10TDP1PTGS1CMA1
Moxalactam SCHEMBL49015 0.99 HSD17B10 (1.00) HSD17B10TDP1PTGS1CMA1
Moxalactam SCHEMBL3511220 0.93 HSD17B10 (0.88) HSD17B10TDP1PTGS1CMA1
Moxalactam SCHEMBL951857 0.89 PTGS1 (0.99) HSD17B10TDP1PTGS1CMA1
Moxalactam SCHEMBL10694935 0.89 PTGS1 (0.99) HSD17B10TDP1PTGS1CMA1
Moxalactam SCHEMBL951858 0.89 PTGS1 (0.99) HSD17B10TDP1PTGS1CMA1
Moxalactam SCHEMBL584454 0.89 PTGS1 (0.99) HSD17B10TDP1PTGS1CMA1
Moxalactam SCHEMBL9800360 0.88 PTGS1 (0.97) HSD17B10TDP1PTGS1CMA1
Moxalactam SCHEMBL194013 0.88 PTGS1 (1.00) HSD17B10TDP1PTGS1CMA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4393512-B1 COMPOSITION FOR PHARMACEUTICAL TABLET, PHARMACEUTICAL TABLET USING THE SAME, AND MANUFACTURING METHOD THEREOF MITSUBISHI CHEM CORP (JP) 2025-10-01 EP disclosed
EP-4393512-A1 COMPOSITION FOR MEDICINAL TABLET, MEDICINAL TABLET OBTAINED USING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Chemical Corporation (JP) 2024-07-03 EP disclosed
US-20240173260-A1 COMPOSITION FOR PHARMACEUTICAL TABLET, PHARMACEUTICAL TABLET USING THE SAME, AND MANUFACTURING METHOD THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2024-05-30 US disclosed
EP-3607084-B1 A METHOD FOR TESTING ANTIMICROBIAL SUSCEPTIBILITY UNIV WESTERN AUSTRALIA (AU) 2024-05-01 EP disclosed
EP-4316469-A1 COMPOSITION FOR SUSTAINED-RELEASE SOLID PREPARATION, SUSTAINED-RELEASE TABLET USING SAME AND MANUFACTURE METHOD THEREOF Mitsubishi Chemical Corporation (JP) 2024-02-07 EP disclosed
US-20240000712-A1 COMPOSITION FOR SUSTAINED-RELEASE SOLID DOSAGE FORM, SUSTAINED-RELEASE TABLET USING THE SAME, AND MANUFACTURING METHOD THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2024-01-04 US disclosed
WO-2022202138-A1 COMPOSITION FOR SUSTAINED-RELEASE SOLID PREPARATION, SUSTAINED-RELEASE TABLET USING SAME AND MANUFACTURE METHOD THEREOF 三菱ケミカル株式会社 2022-09-29 WO disclosed
CN-113387960-B Refining method of latamoxef sodium intermediate 海南海灵化学制药有限公司 2022-04-22 CN disclosed
US-20210292807-A1 METHOD FOR TESTING ANTIMICROBIAL SUSCEPTIBILITY THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2021-09-23 US disclosed
CN-113387960-A Refining method of latamoxef sodium intermediate 海南海灵化学制药有限公司 2021-09-14 CN disclosed
CN-109485659-B Process for preparing 7 alpha-alkoxyoxycephalosporane intermediates 东都股份有限公司 2021-09-10 CN disclosed
EP-3607084-A1 A METHOD FOR TESTING ANTIMICROBIAL SUSCEPTIBILITY The University Of Western Australia (AU) 2020-02-12 EP disclosed
WO-2018184073-A1 A METHOD FOR TESTING ANTIMICROBIAL SUSCEPTIBILITY THE UNIVERSITY OF WESTERN AUSTRALIA (AU) 2018-10-11 WO disclosed