Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Moxalactam. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.80 |
| ▸ | CMA1 | P23946 | 18/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Moxalactam SCHEMBL49015 | 1.00 | HSD17B10 (1.00) | HSD17B10TDP1PTGS1CMA1 | |
| Moxalactam SCHEMBL719333 | 1.00 | HSD17B10 (1.00) | HSD17B10TDP1PTGS1CMA1 | |
| Moxalactam SCHEMBL20528908 | 0.99 | HSD17B10 (0.99) | HSD17B10TDP1PTGS1CMA1 | |
| Moxalactam SCHEMBL3511220 | 0.94 | HSD17B10 (0.88) | HSD17B10TDP1PTGS1CMA1 | |
| Moxalactam SCHEMBL194013 | 0.89 | PTGS1 (1.00) | HSD17B10TDP1PTGS1CMA1 | |
| Moxalactam SCHEMBL14196602 | 0.89 | PTGS1 (1.00) | HSD17B10TDP1PTGS1CMA1 | |
| Moxalactam SCHEMBL49016 | 0.89 | PTGS1 (1.00) | HSD17B10TDP1PTGS1CMA1 | |
| Moxalactam SCHEMBL194012 | 0.89 | PTGS1 (1.00) | HSD17B10TDP1PTGS1CMA1 | |
| Moxalactam SCHEMBL49017 | 0.89 | PTGS1 (1.00) | HSD17B10TDP1PTGS1CMA1 | |
| Moxalactam SCHEMBL951858 | 0.88 | PTGS1 (0.99) | HSD17B10TDP1PTGS1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250250647-A1 | STABLE CELL CLONES HARBORING REPLICATING SARS-COV-2 RNA | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN (US) | 2025-08-07 | — | — | US | disclosed |
| WO-2023027056-A1 | COMPOSITION FOR MEDICINAL TABLET, MEDICINAL TABLET OBTAINED USING SAME, AND PRODUCTION METHOD THEREFOR | 三菱ケミカル株式会社 | 2023-03-02 | — | — | WO | disclosed |